Chapter 12 lecture 3 soft tissue tumors Flashcards Preview

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Flashcards in Chapter 12 lecture 3 soft tissue tumors Deck (49):
1

What is multiple endocrine neoplasia characterized by?

-Parathyroid tumors
-Pituitary tumors
-Pancreatic tumors
-Adrenal gland tumors
-Thyroid tumors
-Mucosal neuromas

2

What are adrenal gland tumors also known as?

-Pheochromocytoma

3

What are thyroid tumors also known as?

-Medullary carcinoma

4

Patients with multiple endocrine neoplasia have what type of build?

-Marfanoid build (long thin face)
-Elongated limbs

5

What is the typically the first sign of multiple endocrine neoplasia?

-Oral mucosal neuromas

6

What are bilateral neuromas of the commissural mucosa highly characteristic of?

-Multiple endocrine neoplasia

7

What is a rare pigmented tumor that usually occurs during the 1st year of life?

-Melanotic neuroectodermal tumor of infancy

8

What does a melanotic neuroectodermal tumor of infancy appear as clinically?

-Black and or blue rapidly expanding mass usually found on the anterior maxilla

9

How do they diagnose melanotic neuroectodermal tumor of infancy?

-Test for high urinary levels of vanillymandelic acid

10

What is a granular cell tumor?

-Benign soft tissue neoplasm that shows a predilection for the oral cavity

11

What is the most common site for a granular cell tumor?

-Tongue with the dorsal surface being the most common

12

What does a granular cell tumor appear as clinically?

-Yellow or mucosal colored, asymptomatic sessile nodule that is less than than 2 cm.

13

What can a granular cell tumor cause?

-Pseudoepitheliomatous hyperlasia (also caused by blastomycosis)

14

What is S-100 positive associated with: granular cell tumor or congenital epulis?

-Granular cell tumor

15

What can occur almost exclusively on the alveolar ridge of newborns?

-Congenital epulis

16

What does a congenital epulis appear as clinically?

-Mucosal colored, smooth surfaced, polypoid mass typically less than 2 cm

17

What arch do you typically see a congenital epulis?

-Maxillary on the ridge

18

What differentiates a congenital epulis from a granular cell tumor?

-a congenital epulis does not have PEH (pseudoepithelomatous hyperlasia) and is S-100 negative

19

What gender does a congenital epulis most commonly occur in?

-Female

20

What is the most common tumor of infancy?

-Hemangioma

21

What is the most common location for a hemangioma?

-Head and neck

22

What are the two types of hemangiomas?

-Capillary
-Cavernous

23

What might you do to tell if it is a capillary hemangioma?

-May not blanch clinically and is usually red in color

24

What might you do to tell if it is a cavernous hemangioma?

-Typically blanches, and is a darker red to purple color

25

What is a rare, nonhereditary developmental condition caused by the persistence of a vascular plexus around the cephalic portion of the neural tube?

-Sturge-Weber Angiomatosis

26

Patients with sturge-weber angiomatosis are born with a dermal capillary vascular malformation known as what?

-Port wine stain
-Nevus flammeus

27

T/F if a pt has port wine stain they have sturge-weber angiomatosis

False
-Not all people with the stain have sturge weber angiomatosis

28

T/F Sturge-weber angiomatosis is unilateral and is usually associated with the trigeminal nerve

True

29

What is a benign tumor of lymphatic vessels?

-Lymphangioma

30

What are the types of lymphangioma?

-Capillary
-Cavernous
-Cystic

31

Where are cavernous lymphangiomas more frequently found?

-In the mouth

32

What are cystic lymphangiomas most often found?

-Lateral Neck

33

Oral lymphangiomas occur most frequently where?

-Anterior two thirds of the tongue resulting often in macroglossia

34

What age do most cases of lymphangiomas occur?

-Before 2 yrs of age

35

What is a benign tumor of smooth muscle?

-Leiomyoma

36

What is the most common location of Leiomyoma?

-Uterus
-GI tract
-Skin

37

What is a benign neoplasm of skeletal muscle?

-Rhabdomyoma

38

Who does the adult type of Rhabdomyoma occur in?

-Men

39

In adult Rhabdomyoma where does it most commonly occur?

-Pharynx
-FOM

40

In fetal Rhabdomyoma who and where does it occur?

-Young male pts
-Predilection for the face

41

What are six soft tissue sarcomas?

-Fibrosarcoma
-Malignant fibrous histiocytoma
-Liposarcoma
-Leiomyosarcoma
-Angiosarcoma
-Malignant peripheral nerve sheath tumor

42

What are the four clinical presentations of Kaposi's sarcoma?

-Classic
-Endemic
-Iatrogenic immunosuppression associated
-AIDS related

43

What ethnicities can get the classic kaposi's sarcoma?

-Italian
-Jewish
-Slavic descent

44

Where is the endemic type of kaposi's sarcoma found?

-Africa

45

What is a malignancy of skeletal muscles?

-Rhabdomyosarcoma

46

Where are the most common locations of Rhabdomyosarcoma?

-Face and orbit in children

47

Head and neck metastases in the absence of lung metastases is possible because of what?

-Batson's plexus

48

What is Batson's plexus?

-Valveless vertebral venous plexus that might allow retrograde spread of tumor cells and bypass the lungs

49

What is the most common site for metastases to the soft tissues?

-Gingiva