Chapter 14 lecture 2 Flashcards

1
Q

What is a diverse group of processes characterized by replacement of normal bone by fibrous tissue containing a mineralized product?

A

-Fibro-Osseous lesions

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2
Q

What are some examples of benign fibro-osseous lesions?

A
  • Fibrous dysplasia
  • Cemento-osseous dysplasia
  • Ossifying fibroma
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3
Q

What is characterized by replacement of normal bone by fibrous connective tissue intermixed with bone that is a sporadic condition resulting from a postzygotic mutation?

A

-Fibrous dysplasia

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4
Q

What is the chief radiographic feature of fibrous dysplasia?

A

-Fine ground glass opactification

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5
Q

What are the two syndromes found in the polyostotic fibrous dysplasia?

A
  • Jaffe-Lichtenstein syndrome

- McCune-Albright Syndrome

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6
Q

What is the most common type of fibrous dysplasia?

A

-Monostotic in the maxilla

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7
Q

When is monostotic fibrous dysplasia usually diagnosed?

A

-Teenage years

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8
Q

What is the most common feature of monostatic fibrous dysplasia?

A

-Slowly growing swelling of the affected area

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9
Q

What do you see in Jaffe-Lichtenstein syndrome?

A
  • Polyostotic fibrous dysplasia

- Cafe au lait spots (Coast of Maine)

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10
Q

What do you see in McCune-Albright syndrome?

A
  • Polyostotic fibrou dysplasia
  • Cafe au laite spots (Coast of maine)
  • Multiple endocrinopathies
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11
Q

Where does cemento-osseous dysplasia occur?

A

-Tooth bearing areas of the Jaw

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12
Q

What is the most common fibro-osseous lesion encountered in clinical practice?

A

-Cemento-Osseous dysplasia

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13
Q

What are the three types of cemento-osseous dysplasia?

A
  • Focal
  • Periapical
  • Florid
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14
Q

What does focal-Cemento-osseous dysplasia exhibit?

A

-Single sight of involvement

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15
Q

Where is the most common place of focal cemento-osseous dysplasia?

A

-Posterior mandible

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16
Q

Who do you see periapical cemento-osseous dysplasia in?

A

-Female African americans around 40

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17
Q

Where do you see periapical cemento-osseous dysplasia?

A

-Periapical region of the anterior mandible

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18
Q

What is florid cemento-osseous dysplasia?

A

-Multiple focal involvement not limited to the anterior mandible

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19
Q

Is cemento-osseous dysplasia symptomatic?

A

-No

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20
Q

Who do you see florid cemento-osseous dysplasia in?

A

-Female African Americans

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21
Q

What might extraction of a tooth in a person with florid COD lead to?

A

-Necrosis

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22
Q

What type of cemento-osseous dysplasia do you biopsy?

A

-Focal

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23
Q

What is an ossifying fibroma?

A

-True neoplasm with significant growth potential

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24
Q

What do early lesions of Cemento-osseous dysplasia appear as?

A

Radiolucent

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25
What do middle lesions of cemento-osseous dysplasia appear as?
-Radiolucent with Radioopacitiy
26
What has large ossifying fibromas of the mandible demonstrate a characteristic downward bowing of the inferior cortex of the mandible?
-Ossifying fibroma
27
How do you distinguish between juvenile ossifying fibroma from an ossifying fibroma?
- Age of patient - Most common sites of involvement - Clinical behavior
28
Where does juvenile ossifying fibromas occur more commonly?
-Maxilla
29
Who does juvenile ossifying fibromas occur more commonly in?
-Males
30
Where does ossifying fibromas occur more commonly?
-Mandible
31
Who does ossifying fibromas occur more commonly in?
-Females
32
What is an osteoma?
-Benign tumors of mature bone
33
Where is an osteoma restricted to?
-Craniofacial skeleton
34
Where does osteoma arise on?
-Surface of bone or within medullary bone
35
T/F Osteomas exhibit continued growth
True
36
What characterizes Gardner syndrome?
- Clonic polyps - Skeletal abnormalities - Dental abnormalities - Epidermoid cysts - Dermoid tumors - Thyroid carcinoma - Pigmented lesions of the ocular fundus
37
In Gardner syndrome what will bowel polyps transform into?
-Adenocarcinoma
38
What skeletal abnormalities do you most commonly see in Gardner syndrome?
-Osteomas
39
What dental abnormalities do you see in Gardner syndrome?
- Supernumerary teeth - Impacted teeth - Odontomas
40
What treatment do you need to do in Gardner syndrome?
-Prophylactic colectomy
41
What are closely related benign bone tumors?
- Osteoblastoma | - Osteoid Osteoma
42
What does osteoid osteoma produce?
-Prostaglandins
43
What is the pain relieved by in osteoid osteoma?
-Aspirin
44
What are the size of osteoid osteomas?
-Smaller than 2 cm
45
What are the size of osteoblastomas?
-Larger than 2 cm
46
T/F Osteoblastomas are painful
True
47
What type of pain do you see in osteoid osteoma?
-Nocturnal
48
What is a cementoblastoma?
-Odontogenic neoplasm of cementoblasts
49
Where do most cementoblastomas occur?
-Mandible in the molar/premolar region
50
If you can see the root outline/PDL in the radioopacity will it be a cementoblastoma?
-No
51
What is a chondroma?
-Benign tumor of cartilage
52
T/F Synovial chondromatosis is a rare, benign , non neoplastic tumor
True
53
Where does synovial chondromatosis most commonly affect?
-Large joints but can affect the TMJ
54
What are some common features of synovial chondromatosis?
- Swelling - Pain - Crepitus - Limitation of motion
55
What do you see in an XRAY in someone with synovial chondromatosis?
-Loose bodies
56
What is an osteosarcoma?
-Mesenchymal malignancy
57
If you exclude hematopoietic neoplasma what is the most common type of malignancy to originate within bone?
-Osteosarcoma
58
Whais the most common malignancy of bone?
-Metastatic disease
59
Extragnathic osteosarcomas have a bimodal age distrubution, when does it occur?
- 10-20 yrs most common | - After 50
60
What is the most common place for osteosarcomas to arise in young pts?
- Distal femur | - Proximal tibia
61
When do ostosarcomas of the jaw occur?
-around age 33
62
In an XRAY you see a sunburst appearance, what should you be thinking of?
-Osteosarcoma
63
A triangular elevation of periosteum associated with osteosarcoma is termed what?
-Codman's triangle
64
Root resorption which is termed spiking resorption is associated with what?
-Osteosarcoma
65
What is a Juxtacortical osteosarcoma aka?
-Peripheral osteosarcoma
66
What is a chondrosarcoma?
-Malignant bone tumor of cartilage
67
What is ewing sarcoma?
-Primary malignant tumor of bone
68
What is the 3rd most common osseous neoplasm?
-Ewing sarcoma
69
If you see the onionskin in an XRAY what are you thinking of?
-Ewing sarcoma
70
What is the most common form of cancer involving bone?
-Metastatic tumor
71
What are the most common origins of Gnathic mets?
- Breast - Lung - Thyroid - Prostate - Kidney
72
What is a numb-chin syndrome associated with?
-Metastatic tumor
73
If you see the moth-eaten feature in an XRAY what are you thinking?
-Metastatic tumor