Chapter 19- Table 19.4 Flashcards
Which gene is commonly mutated in Peutz-Jeghers syndrome
STK11
Which gene is commonly mutated in hereditary pancreatitis
PRSS1,SPINK1
Which gene is commonly mutated in familial multiple-mole melanoma
CDK2NA
What is the marker CA19-9 antigen used to help diagnosis
Pancreatic cancer
Which gene is commonly mutated in hereditary and ovarian cancer presdisposing to pancreatic cancer
BRCA, PALP2
Which gene is commonly mutated in hereditary non-polyposis colorectal cancer (HNPCC)
MLH, MSH
What disorder has the highest predisposing risk to pancreatic cancer
Peutz-Jeghers syndrome
What is the increased predisposed risk amount for pancreatic cancer with the condition Peutz-Jeghers syndrome
130 times
What is the increased predisposed risk amount for pancreatic cancer with the condition hereditary pancreatitis
50-80 times
What is the increased predisposed risk amount for pancreatic cancer with the condition mole melanoma syndrome
20-35
