Chapter 20 Flashcards

pathogenic gram - organism

1
Q

what is the enterobacteriaceae

A

an intestinal microbiota of most animals and humans

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2
Q

where is the enterobacteriaceae found

A

in water, soil, and decaying vegetation

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3
Q

major virulence factor of enterobacteriaceae

A

type III secretion system.

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4
Q

what does T3SS do

A

injects effector molecules into host cell

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5
Q

pathogenic enterobacteriacea include what

A

yersinia and salmonella

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6
Q

yersinia causes what

A

bubonic plague and pnemonic plague

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7
Q

where is salmonella enterica found

A

in intestines of birds, reptiles, and mammals

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7
Q

is yersinia virulent? if yes.. how?

A

yes, very
has t3ss and injects a yersinia outer protein into host cells
the YPOS then causes apoptosis (cell death) of macrophages and neutrophils

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8
Q

how does salmonella enterica infect host

A

enters host cells for intercullular replication and eventually kills host cell

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9
Q

virulence factor of salmonella

A

t3ss
it can also survive in a macrophage and inhibit lysosome fusion or perform intracellular replication

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10
Q

how do humans usually get salmonells

A

consuming contaminated food like poultry and eggs

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11
Q

what do coliforms look like

A

gram negative,, rod shaped bacteria

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12
Q

what do coliforms ferment

A

lactose to form gas

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13
Q

where are coliforms found

A

in the intestinal tracts of animals and humans

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14
Q

what are coliforms used for

A

they are indicater organisms to indicate impure water

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15
Q

what is the most common coliform

A

escherichia coli

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16
Q

what do virulent strains of ecoli have

A

virulence factors like plasmids (adhesins, exotoxins)

17
Q

ecoli O157 : H7 is what

A

a specific antigen prevalet in developed countires. comes from undercooked beef, contaminated milk or fruit juice

18
Q

virulence factors of ecoli O157 H7

A

t3ss and shiga-toxin

19
Q

hemolytic uremic syndrome is from what

A

ecoli O157 :H7

20
Q

what do shiga toxins do

A

affect blood and blood vessels

21
Q

what does hemolytic uremic syndrome do

A

affects intestines and kidneys and destroys blood platelets and disrupts normal blood clotting process

22
Q

what is klebsiella

A

a coliform

23
Q

where is klebsiella found

A

in digestive and respitory tracts of humans and animals

24
Q

what does klebsiella use to prevent phagocytosis

A

capsule

25
Q

is kelbsiella opportunistic

A

yes

26
Q

whats the most ocmmon klebsiella

A

k pneumoniae

27
Q

what does k. pneumoniae do

A

causes pneumonia , enters blood , wound infections, and UTIs

28
Q

what are the 3 types of aerobic bacilli

A

bordetella
pseudomonads
francisella

29
Q

bordella looks like what

A

nonmotile coccobacillus

30
Q

main type of bordella

A

b. pertussis

31
Q

what does b pertussis casue

A

pertussis or whooping cough

32
Q

what are the 3 adhesions and toxins that b pertussis uses

A

pertussis toxin to inhibit macrophages and nuetrophil recruitement
adenylate cyclase toxin to inhibit phagocytosis
tracheal cytotoxin to damage respitroy tract cells

33
Q

main type of psuedomonads

A

pseudomonas aeruginosa

34
Q

is pseudomonads aeruginosa a part of the normal human microbiota

A

rarely

35
Q

biofilms in pseudomasas aeruginosa allows for what

A

a protection layer, cell adaptation, alter chemical micro-environment, persistence cells

36
Q

main types of francisella

A

francisella tularensis

37
Q

what do francisella tularensis look like

A

non moticle, strictly aerobic coccobacillus

38
Q

what is francisella tularensis an intracellular parasite of

A

of animals and amoebae in water

39
Q

what infection does francisella tularensis cause

A

tularemia

40
Q

info on tularemia

A

bsl 3
spread through bite of an infected tick or contact with an infected animal, also spread by bacteria in meat, water, and in aerosols, highly infectious

41
Q
A