Chapter 20 - Anxiolytic and Hypnotic Agents Flashcards Preview

Nur 30 Pharmacology > Chapter 20 - Anxiolytic and Hypnotic Agents > Flashcards

Flashcards in Chapter 20 - Anxiolytic and Hypnotic Agents Deck (8):
1

Diazepam (I)

Benzodiazepine

Management of...
Acute Anxiety Disorders
Acute Alcohol Withdrawal
Muscle Relaxation
Tetanus
Antiepileptic in status epilepticus
Preoperative relief of anxiety and tension

2

Diazepam (A)

Acts in the limbic system and reticular formation to potentiate the effects of GABA, may act in spinal cord and supraspinal sites to produce muscle relaxation.

3

Diazepam (AE)

Mild drowsiness
Depression
lethargy
changes in libido
drug dependence
incontinence

4

Diazepam (CI - DD)

CI: Narrow angle glaucoma
Shock
Coma
Acute alcoholic intoxication
Neonatal Withdrawal syndrome may result

DD: Alcohol
Effects increase with oral contraceptives

5

Phenobarbital (I)

Barbiturate

Sedation
Short term treatment of insomnia
long term treatment of tonic clonic seizures
Cortical focal seziures
Emergency control of acute convulsive episodes
preanesthetic

6

Phenobarbital (A)

Inhibits conduction in the ascending RAS
Depresses the cerebral cortex
Alters cerebellar function
Depresses motor output
Can produce excitation, sedation, hypnosis, anesthesia, and deep coma; and has anticonvulsant activity

7

Phenobarbital (AE)

Somnolence
Hyperkinesias
ataxia
Stevens Johnsonsyndrome
Withdrawal syndrome

8

Phenobarbital (CI-DD)

CI: Hx of addiction
Manifest porphyria
Resp distress

DD: Alcohol, antihistamines
MAO inhibitors ^effects
Oral anticoags
digoxin
Oral contraceptives
BBlockers