Chapter 23 drugs for neurological disorders Flashcards Preview

Nursing > Chapter 23 drugs for neurological disorders > Flashcards

Flashcards in Chapter 23 drugs for neurological disorders Deck (21):
0

The drug prescribed to treat Parkinsonism by replacing the neurotransmitter
Carbidopa or levodopa

Levodopa

1

Examples of ACE inhibitors

Tacrine
Cognex
Aricept
Exelon

2

Which drug prolongs action of levodopa and can decrease on-off fluctuations in patients with Parkinsonism

Selegiline

3

Initial dose of carbidopa and levodopa

10/100 mg tid/qid

4

Maintenance dose of carbidopa levodopa

25/250 tid/qid

5

Possible side effect of carbidopa levodopa
Diarrhea
Anxiety
Nasal stuffiness
Dizziness

Dizziness

6

Foods that should be avoided when taking selegiline (Eldepryl)

Aged cheeses
Chocolate
Yogurt
These food are high in Tyramine which may cause hypertensive crisis

7

What decreases the effect of rivastigmine
Atypical antidepressants
SSRI
Tricyclics


TRICYCLICS

8

Selected drugs to treat Parkinson's or pseudo

Cogentin
Artane
Akineton
Benadryl

9

Side effects of antiparkinsonism-anticholinergics

Red as a beet
Dry as a bone
Mad as a hatter
Hot as a hare
Can't see
Can't pee
Can't spit
Can't shit
Nausea and vomiting
Postural hypotension

10

Contraindications of antiparkinsonism-anticholinergics

Glaucoma
GU obstruction
BPH

11

Side effects of levodopa

Gi upset
Dyskinesia
Dystonic movements orthostasis hypotension
Cardiac dysrhythmias
Psychosis
Agranulocytosis - most serious side effect

12

What is benefit of drug combination of carbidopa and levodopa (Sinemet)

Allows more dopamine to reach the brain
Allows once a day dosing
Smaller doses of levodopa are required to achieve desired effect

13

Name some dopamine agonists (stimulate dopamine receptors)

Symmetrel
Parlodel
Mirapex
Requip
Neupro

14

Name MAO-B inhibitors

Selegiline
Rasagline

15

Name COMT inhibitors

Tolcarpone - monitor LFTs
Entacopone

16

With Parkinson's drugs what vitamin do you need to limit

Vitamin B6 to normal doses
Dried beans, certain cereals

17

Name characteristics of myasthenia gravis

Muscular weakness and fatigue
Resp muscle paralysis
Ptosis
Difficulty chewing and swallowing

18

Pathophysiology of MG

Lack of acetylcholine reaching cholinergic receptors

19

What meds is MG treated with

AChe inhibitor

20

Normal dose of namenda

10 mg morning and night