Chapter 46: Renal/Urologic Flashcards Preview

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Flashcards in Chapter 46: Renal/Urologic Deck (82)
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1
Q

CULTURAL & ETHNIC HEALTH DISPARITIES

A
  • Urinary tract calculi are more common among whites than African Americans.
  • Uric acid stones are more common in Jewish men.
  • Bladder cancer has a higher incidence among white men than African American men.
  • In all ethnic groups, bladder cancer affects men about three times more often than women.
  • Urinary incontinence is underreported because culturally it is seen as a social hygiene problem causing patient embarrassment.
2
Q

Escherichia coli is the most common pathogen causing a UTI

A

and is primarily seen in women. Bacterial counts
of 105 colony-forming units per milliliter (CFU/mL) or higher typically indicate a clinically significant UTI. However, counts as low as 102 to 103 CFU/mL in a person with signs and symptoms
are indicative of UTI.

3
Q

Specific terms

are used to further delineate the location of a UTI. For example

A

pyelonephritis implies inflammation (usually caused by infection) of the renal parenchyma and collecting system, cystitis indicates inflammation of the bladder, and urethritis means inflammation of the urethra. Urosepsis is a UTI that has spreadsystemically and is a life-threatening condition requiring emergency
treatment

4
Q

Lower urinary tract symptoms (LUTS) are experienced in
patients who have UTIs of the upper urinary tract, as well as those confined to the lower tract. Symptoms are related to either bladder storage or bladder emptying.

A

dysuria, frequent urination (more than every 2 hours), urgency, and suprapubic discomfort or pressure. The urine may contain grossly visible blood (hematuria)
or sediment, giving it a cloudy appearance. Flank pain,
chills, and fever indicate an infection involving the upperurinary tract (pyelonephritis)

5
Q

UTI, initially obtain a dipstick urinalysis to identify the presence of nitrites (indicating bacteriuria), white blood cells (WBCs), and leukocyte esterase (an enzyme present in WBCs indicating pyuria). These findings can be confirmed by microscopic urinalysis.

A

After confirmation of bacteriuria and pyuria, a urine culture may be obtained. A urine culture is indicated in complicated or HAI UTIs, persistent bacteriuria, or frequently recurring UTIs (more than two or three episodes per year). Urine may also be cultured when the
infection is unresponsive to empiric therapy or the diagnosis is questionable

6
Q

First-choice drugs to empirically treat uncomplicated or

initial UTIs are

A

trimethoprim/sulfamethoxazole (TMP/SMX)
(Bactrim, Septra), nitrofurantoin (Macrodantin), and fosfomycin (Monurol). TMP/SMX has the advantages of being relatively inexpensive and being taken twice daily.

7
Q

treat complicated UTIs.

A

These drugs include ciprofloxacin (Cipro), levofloxacin (Levaquin), norfloxacin (Noroxin), ofloxacin (Floxin), and gatifloxacin (Tequin). In patients with UTIs secondary to fungi, amphotericin or fluconazole (Diflucan) is the preferred therapy.

8
Q

DRUG ALERT: Nitrofurantoin (Furadantin, Macrodantin)

A

• Avoid sunlight. Use sunscreen, and wear protective clothing.
• Notify health care provider immediately if fever, chills, cough,
chest pain, dyspnea, rash, or numbness or tingling of fingers or toes
develops.

9
Q

Nursing diagnoses for the patient with a UTI may include, but are not limited to, the following: pg 1067

A
  • Impaired urinary elimination related to the effects of UTI

* Readiness for enhanced self-health management

10
Q

Health promotion activities include teaching preventive measures such as

A

(1) emptying the bladder regularly and completely, (2) evacuating th bowel regularly, (3) wiping the perineal area from front to back after urination and defecation, and (4) drinking an adequate amount of liquid each day.

11
Q

It is important to recognize individuals

who are at risk for a UTI. These people include

A

debilitated persons, older adults, patients who are immunocompromised (e.g., cancer, human immunodeficiency virus [HIV], diabetes mellitus), and patients treated with immunosuppressive drugs
or corticosteroids.

12
Q

Teach patients to promptly report any of the following to their health care provider:

A

(1) persistence of bothersome LUTS beyond the antibiotic

treatment course, (2) onset of flank pain, or (3) fever

13
Q

Pyelonephritis usually begins with colonization and infection of the lower urinary tract via the ascending urethral route.
Bacteria normally found in the intestinal tract, such as E. coli or Proteus, Klebsiella, or Enterobacter species, frequently cause pyelonephritis.

A
A preexisting factor is often present such as
vesicoureteral reflux (retrograde, or backward, movement of urine from lower to upper urinary tract) or dysfunction of the lower urinary tract (e.g., obstruction from benign prostatic hyperplasia [BPH], a stricture, a urinary stone).
14
Q

Ultrasonography of the urinary system may be performed

to identify anatomic abnormalities,

A

hydronephrosis, renal abscesses, or an obstructing stone.

CT urograms are also used to assess for signs of infection in the kidney and complications of yelonephritis, such as impaired renal function, scarring,
chronic pyelonephritis, or abscesses.

15
Q

The overall goals are that the patient with pyelonephritis will have

A

(1) normal renal function, (2) normal body temperature,

(3) no complications, (4) relief of pain, and (5) no recurrence of symptoms.

16
Q

In chronic pyelonephritis the kidneys become small, atrophic, and shrunken and lose function due to fibrosis (scarring).

A

Radiologic imaging and a biopsy, rather than clinical features, are used to confirm the diagnosis of chronic pyelonephritis. Imaging studies reveal a small, fibrotic kidney. The collecting system may be small or hydronephrotic. Biopsy results indicate the loss of functioning nephrons, infiltration of the parenchyma
with inflammatory cells, and fibrosis.

17
Q

Urethritis is an inflammation of the urethra. Causes of urethritis include

A
a bacterial or viral infection, Trichomonas and
monilial infection (especially in women), chlamydial infection, and gonorrhea (especially in men).
18
Q

Urethral diverticula are localized outpouchings of the urethra.

A

Most often they result from enlargement of obstructed periurethral glands.

19
Q
Interstitial cystitis (IC) is a chronic, painful inflammatory
disease of the bladder characterized by symptoms of urgency, frequency, and pain in the bladder and/or pelvis.
A

Painful bladder syndrome (PBS) is suprapubic pain related to bladder filling.
The term IC/PBS refers to cases of urinary pain that cannot be attributed to other causes such as infection or urinary calculi.

20
Q

Because the etiology of IC/PBS is unknown, no single treatment consistently reverses or relieves symptoms. Various therapies have been effective, including nutritional and drug therapy.18,19 Surgical therapy is rarely indicated.

A

Elimination of foods and beverages that are likely to irritate the bladder may provide some relief from symptoms. Typical bladder irritants include caffeine; alcohol; citrus products; aged cheeses; nuts; foods containing vinegar, curries, or hot peppers; and foods or beverages, including fruits (cranberries), likely to
lower urinary pH.

21
Q

The clinical manifestations of APSGN include

Acute poststreptococcal glomerulonephritis (APSGN)

A

generalized body edema, hypertension, oliguria, hematuria with a smoky or rusty appearance, and proteinuria.

22
Q

The diagnosis of APSGN is based on a complete history and physical examination.

A

Dipstick urinalysis and urine sediment microscopy reveal
erythrocytes in significant numbers. Erythrocyte casts are
highly suggestive of APSGN. Proteinuria may range from mild to severe. Blood tests include blood urea nitrogen (BUN) and serum creatinine to assess the extent of renal impairment.

23
Q

One of the most important ways to prevent APSGN is to
encourage early diagnosis and treatment of sore throats and
skin lesions.

A

If streptococci are found in the culture, treatment
with appropriate antibiotic therapy (usually penicillin) is essential. Encourage the patient to take the full course of antibiotics to ensure that the bacteria have been eradicated. Good personal hygiene is an important factor in preventing the spread of cutaneous streptococcal infections

24
Q

Goodpasture syndrome is an autoimmune disease characterized by circulating antibodies against glomerular and alveolar basement membrane.

A

Damage to the kidneys and lungs results when binding of the antibody causes an inflammatory reaction mediated by complement activation

25
Q

Goodpasture syndrome is a rare disease that is mostly found in young male smokers. The clinical manifestations include

A

flulike symptoms with pulmonary symptoms such as cough, mild shortness of breath, hemoptysis, crackles, rhonchi, and pulmonary insufficiency. Renal involvement causes hematuria, weakness, pallor, anemia, and renal failure. Pulmonary hemorrhage usually occurs and may precede glomerular abnormalities by
weeks or months.

26
Q

RPGN can occur in a variety of situations:

A

(1) as a complication
of inflammatory or infectious disease (e.g., APSGN), (2) as
a complication of a systemic disease (e.g., systemic lupus erythematosus),
(3) as an idiopathic disease, or (4) with the use of
certain drugs (e.g., penicillamine).

27
Q

Nephrotic syndrome results when the glomerulus is excessively permeable to plasma protein, causing proteinuria that leads to low plasma albumin and tissue edema.

A

Immune responses, both humoral and cellular, are altered
in nephrotic syndrome. As a result, infection is a primary
cause of morbidity and mortality. Calcium and skeletal abnormalities may occur, including hypocalcemia, blunted calcium response to parathyroid hormone, hyperparathyroidism, and osteomalacia.

28
Q

Crystals, when in a supersaturated concentration, can precipitate and unite to form a stone.

A

A mucoprotein is formed in the kidneys as a matrix for the stone. Urinary pH, solute load, and inhibitors in the urine affect the formation of stones. The higher the pH (alkaline), the less soluble are calcium and phosphate. The lower the pH (acidic), the less soluble are uric acid and cystine. When a substance is not very soluble in fluid, it is more likely to precipitate out of solution

29
Q

The term calculus refers to the stone, and lithiasis refers to stone
formation. The five major categories of stones are

A

(1) calcium
phosphate, (2) calcium oxalate, (3) uric acid, (4) cystine, and
(5) struvite (magnesium ammonium phosphate)

30
Q

Renal colic is the term used for the sharp, severe pain, which results from the stretching, dilation, and spasm of the ureter in response to the obstructing stone. Nausea and vomiting may occur due to the severe pain

A

Urinary stones cause clinical manifestations when they
obstruct urinary flow. Common sites of obstruction are at the UPJ (where the renal pelvis narrows into the ureter) and at the ureterovesical junction (UVJ).

31
Q

Indications for endourologic, lithotripsy, or open surgical

stone removal include the following:

A

(1) stones too large for spontaneous passage (usually greater than 7 mm); (2) stones associated with bacteriuria or symptomatic infection; (3) stones causing impaired renal function; (4) stones causing persistent pain, nausea, or paralytic ileus; (5) inability of patient to be treated medically; and (6) patient with only one kidney.

32
Q

Purine*

uric acid is by product

A

High: Sardines, herring, mussels, liver, kidney, goose, venison, meat soups, sweetbreads Moderate: Chicken, salmon, crab, veal, mutton, bacon, pork, beef, ham

33
Q

Calcium

A

High: Milk, cheese, ice cream, yogurt, sauces containing milk; all beans (except green beans), lentils; fish with fine bones (e.g., sardines, kippers, herring, salmon); dried fruits, nuts; Ovaltine, chocolate, cocoa

34
Q

Oxalate

A

High: Dark roughage, spinach, rhubarb, asparagus, cabbage, tomatoes, beets, nuts, celery, parsley, runner beans; chocolate, cocoa, instant coffee, Ovaltine, tea; Worcestershire sauce

35
Q

Nursing diagnoses for the patient with urinary tract calculi

include, but are not limited to, the following: pg 1080

A

• Impaired urinary elimination related to trauma or
obstruction of ureters or urethra
• Acute pain related to effects of stones and inadequate pain control or comfort measures
• Deficient knowledge related to unfamiliarity with information resources and lack of experience with urinary
stones

36
Q

A stricture is a narrowing of the lumen of the ureter or

urethra.

A

Ureteral strictures can affect the entire length of the ureter, from the UPJ to the UVJ. These strictures are usually an unintended result of surgical intervention or secondary to adhesions or scar formation, or they may be due to extrinsic factors such as large tumors in the peritoneal cavity.

37
Q

A urethral stricture is the result of fibrosis or inflammation of the urethral lumen.

A

Causes of urethral strictures include trauma,
urethritis (particularly after gonococcal infection), surgical
intervention or repeated catheterizations (iatrogenic), or a congenital defect of the urethra.

38
Q

Nursing interventions depend on the type of renal trauma

and the extent of any associated injuries. Interventions related to renal trauma include the following:

A

(1) assess the cardiovascular
status and monitor for shock, especially in a penetrating
injury; (2) ensure adequate fluid intake and monitor intake and output; (3) provide for pain relief and comfort measures; and (4) assess for hematuria and myoglobinuria.

39
Q

Vascular problems involving the kidney include

A

(1) nephrosclerosis,

(2) renal artery stenosis, and (3) renal vein thrombosis.

40
Q

Polycystic kidney disease (PKD) is the most common lifethreatening genetic disease in the world, affecting 600,00 people in the United States. PKD accounts for 10% to 15% of chronic kidney disease.26

A

PKD has two hereditary forms: it may be manifested in childhood or adulthood. The childhood form of PKD is a rare autosomal recessive disorder that is often rapidly progressive (see the Genetics in Clinical Practice box). The adult form of PKD is an autosomal dominant disorder

41
Q

Alport syndrome, also known as chronic hereditary nephritis, has two forms:

A

(1) classic Alport syndrome, which is inherited as a
sex-linked disorder with hematuria, sensorineural deafness, and deformities of the anterior surface of the lens; and (2) nonclassic Alport syndrome, which is inherited as an autosomal disorder
that causes hematuria but not deafness or lens deformities.

42
Q

Renal cell carcinoma (adenocarcinoma) is the most common type of kidney cancer

A

smoking and to asbestos, cadmium, and gasoline. Risk for kidney cancer is also increased in individuals who have acquired cystic disease of the kidney associated with ESKD

43
Q

The following is a simple

description of staging of bladder cancer:

A

Stage I: Cancer is in the inner lining of the bladder but has
not invaded the bladder muscle wall.
Stage II: Cancer has invaded the bladder wall but is still
confined to bladder.
Stage III: Cancer has spread through the bladder wall to surrounding
tissue. It may also have spread to the prostate
in men or the uterus or vagina in women.
Stage IV: Cancer has spread to the lymph nodes and other
organs, such as lungs, bones, or liver.

44
Q

The following is a simple description of staging of

kidney cancer:

A

Stage I: The tumor can be up to 7 cm in diameter but is
confined to the kidney.
Stage II: The tumor is larger than a stage I tumor, but is still
confined to the kidney.
Stage III: The tumor extends beyond the kidney to the surrounding
tissue and may also have spread to a nearby
lymph node.
Stage IV: Cancer spreads outside the kidney to multiple
lymph nodes or to distant parts of the body, such as
bones, brain, liver, or lung.

45
Q

urinary incontinence….. Using the acronym DRIP, the causes

can include

A

D: delirium, dehydration, depression; R: restricted

mobility, rectal impaction; I: infection, inflammation, impaction; and P: polyuria, polypharmacy.

46
Q

Measure postvoid residual (PVR) urine in the patient undergoing evaluation for UI.

A

The PVR volume is obtained by asking the patient to urinate, followed by catheterization or use of a bladder ultrasound within a relatively brief period (preferably 10 to 20 minutes).

47
Q

An estimated 80% of incontinence can be cured or significantly
improved

A

therapies…Pelvic floor muscle training (Kegel exercises) is
used to manage stress, urge, or mixed UI

Biofeedback is used to help the patient identify, isolate, contract, and relax the pelvic muscles

drug therapy

SURGERY

48
Q

Stress Incontinence*

A

Pelvic floor muscle exercises (e.g., Kegel
exercises), weight loss if patient is obese,
cessation of smoking, topical estrogen
products, external condom catheters or
penile clamp in men, surgery
Urethral inserts, patches, or bladder neck
support devices (e.g., incontinence pessary)
to correct underlying problem

49
Q

Urge Incontinence*

A

Treatment of underlying cause
Biobehavioral interventions, including bladder
retraining with urge suppression, decrease in
dietary irritants, bowel regularity, and pelvic
floor muscle exercises
Anticholinergic drugs (e.g., oxybutynin
[Ditropan XL, Oxytrol], tolterodine [Detrol,
Detrol LA], trospium chloride [Sanctura],
solifenacin [VESIcare], and darifenacin
[Enablex]); imipramine (Tofranil) at bedtime;
calcium channel blockers
Containment devices (e.g., external condom
catheters)
Vaginal estrogen creams
Absorbent products

50
Q

Overflow Incontinence

A

Urinary catheterization to decompress bladder
Implementation of Credé or Valsalva maneuver
α-Adrenergic blocker (doxazosin [Cardura],
terazosin [Hytrin], tamsulosin [Flomax],
alfuzosin [Uroxatral])
5α-Reductase inhibitors (e.g., finasteride
[Proscar]) to decrease outlet resistance
bethanechol (Urecholine) to enhance bladder
contractions
Intravaginal device such as a pessary to
support prolapse
Intermittent catheterization
Surgery to correct underlying problem

51
Q

Reflex Incontinence

A
Treatment of underlying cause
Bladder decompression to prevent ureteral
reflux and hydronephrosis
Intermittent self-catheterization
diazepam (Valium) or baclofen (Lioresal) to
relax external sphincter
Prophylactic antibiotics
Surgical sphincterotomy
52
Q

Incontinence After Trauma or Surgery

A

Surgery to correct fistula
Urinary diversion surgery to bypass urethra
and bladder
External condom catheter
Penile clamp
Placement of artificial implantable sphincter

53
Q

Functional Incontinence

A

Modifications of environment or care plan that
facilitates regular, easy access to toilet and
promotes patient safety (e.g., better lighting,
removal of scatter rugs, ambulatory
assistance equipment, clothing alterations,
timed voiding, different toileting equipment

54
Q

DRUG ALERT: Tolterodine (Detrol)

A
  • Overdosage can result in severe anticholinergic effects.

* These effects include GI cramping, diaphoresis, blurred vision, and urinary urgency

55
Q

It is important to recognize both the physical and the emotional problems associated with UI. Maintain and enhance the patient’s dignity, privacy, and feelings of self-worth. This is a two-step approach:

A
(1) containment devices to manage existing urinary
leakage and (2) a definitive plan to reduce or resolve the factors leading to UI.
56
Q

Timed voiding

A

Toileting on a fixed schedule (typically every
2-3 hr during waking hours).Toileting on a fixed schedule (typically every
2-3 hr during waking hours).

57
Q

Habit retraining

A

Scheduled toileting with adjustments of voiding
intervals (longer or shorter) based on the
individual’s voiding pattern.

58
Q

Prompted voiding

A

Scheduled toileting that requires prompts to
void from a caregiver (typically every 3 hr).
Used in conjunction with operant conditioning
techniques to reward individuals for maintaining
continence and appropriate toileting

59
Q

Bladder retraining
and urgesuppression
strategies

A

Scheduled toileting with progressive voiding
intervals. Includes teaching of urge-control
strategies using relaxation and distraction
techniques, self-monitoring, reinforcement
techniques, and other strategies such as
conscious contraction of pelvic floor muscles.

60
Q
Intravaginal
support devices
(pessaries and
bladder neck
support
prostheses)
A

Devices support bladder neck, relieve minor
pelvic organ prolapse, and change pressure
transmission to the urethra

61
Q

Intraurethral
occlusive device
(urethral plug)

A

Single-use device that is worn in the urethra to
provide mechanical obstruction to prevent
urine leakage. Removed for voiding.

62
Q

Penile
compression
device

A

Mechanical fixed compression applied to the
penis to prevent any flow or leakage via the
urethra. Must be released hourly to void.

63
Q

Urinary retention is caused by two different dysfunctions of

the urinary system:

A

bladder outlet obstruction and deficient

detrusor (bladder muscle) contraction strength.

64
Q

Role of Registered Nurse (RN)

A

• Assess for risk factors for incontinence or urinary retention.
• Determine type of incontinence that patient is experiencing.
• Develop plan of care to decrease incontinence.
• Teach patient ways to decrease incontinence such as pelvic floor
muscle (Kegel) exercises.
• Assist patient in choosing appropriate products to contain urine.

65
Q

Role of Licensed Practical/Vocational Nurse (LPN/LVN)

A
  • Use bladder scanner to estimate the postvoid residual volume (PVR).
  • Catheterize patient and measure PVR.
  • Administer medications to decrease incontinence or urinary retention.
66
Q

Role of Unlicensed Assistive Personnel (UAP)

A

• Assist incontinent patient to commode or bedpan at regular intervals.
• Clean patient and provide skin care.
• Notify RN about new-onset incontinence in a previously continent
patient.

67
Q

Muscarinic Receptor Antagonists and Anticholinergics

oxybutynin (Ditropan IR, Ditropan

A

Reduce overactive bladder
contractions in urge urinary
incontinence and overactive
bladder

68
Q

α-Adrenergic Antagonists

tamsulosin (Flomax)

A

Reduce urethral sphincter

resistance to urinary outflow

69
Q

5α-Reductase Inhibitors

finasteride (Proscar)
dutasteride (Avodart)

A

Androgen suppression that
results in epithelial atrophy
and a decrease in total
prostate size

70
Q

α-Adrenergic Agonists

phenylpropanolamine
pseudoephedrine

A

Increase urethral resistance

71
Q

β3-Adrenergic Agonist

mirabegron (Myrbetriq)

A

Improves the bladder’s storage
capacity by relaxing the
bladder muscle during filling

72
Q

Tricyclic Antidepressants

imipramine (Tofranil)
amitriptyline (Elavil)

A
Reduce sensory urgency and
burning pain of interstitial
cystitis
Reduce overactive bladder
contractions
73
Q

Calcium Channel Blockers

nifedipine (Adalat)
diltiazem (Cardizem)
verapamil (Calan, Isoptin)

A

Reduce smooth muscle
contraction strength
May reduce burning pain of
interstitial cystitis

74
Q

Hormone Therapy

estrogen cream (Premarin, Estrace)
estrogen vaginal ring (Estring)
estrogen vaginal tablets (Vagifem)

A

Local application reduces
urethral irritation and increases
host defenses against UTI

75
Q

Indwelling Catheter

A

• Relief of urinary retention caused by lower urinary tract obstruction,
paralysis, or inability to void
• Bladder decompression preoperatively and operatively for lower
abdominal or pelvic surgery
• Facilitation of surgical repair of urethra and surrounding structures
• Splinting of ureters or urethra to facilitate healing after surgery or
other trauma in area
• Accurate measurement of urine output in critically ill patient
• Contamination of stage III or IV pressure ulcers with urine that has
impeded healing, despite appropriate personal care for the
incontinence
• Terminal illness or severe impairment, which makes positioning or
clothing changes uncomfortable, or which is associated with
intractable pain

76
Q

Intermittent (Straight, In and Out) Catheter

A

• Study of anatomic structures of urinary system
• Urodynamic testing
• Collection of sterile urine sample in selected situations
• Instillation of medications into bladder
• Measurement of residual urine after urination (postvoid residual
[PVR]) if portable ultrasound not available

77
Q

Complications that are seen more frequently with long-term

use (more than 30 days) of indwelling catheters include

A

HAIs,
bladder spasms, periurethral abscess, pain, urosepsis, UTIs,
urethral trauma or erosion, fistula or stricture formation, and
stones.

78
Q

Role of Registered Nurse (RN)

A

• Determine need for catheterization.
• Choose appropriate type and size of catheter.
• Insert catheter in patient with urethral trauma, pain, or obstruction.
• Develop plan of care to decrease risk for infection in patient with
indwelling catheter.

79
Q

Role of Licensed Practical/Vocational Nurse (LPN/LVN)

A

• Insert intermittent or indwelling catheter for uncomplicated patients.
• Irrigate the catheter if obstruction is suspected in stable patients
(e.g., in long-term care).

80
Q

Role of Unlicensed Assistive Personnel (UAP)

A

• Provide perineal care around the catheter with soap and water.
• Anchor the catheter in place (upper thigh in women and lower
abdomen in men).
• Notify RN about changes in skin condition, especially around
meatus.

81
Q

Catheters are sized according to the French scale

A

The size used
varies with the patient’s size and the purpose of catheterization.
In women, urethral catheter sizes 14F to 16F are the most
common. In men, sizes 14F to 18F are used. Balloon sizes are
either 5 or 30 mL.

82
Q

Urethral catheterization, the most common route of catheterization, involves the insertion of a catheter through the external meatus into the urethra, past the internal sphincter, and into the bladder.

different then……

A

The ureteral catheter is placed through the ureters into the renal
pelvis. The catheter is inserted either (1) by being threaded up
the urethra and bladder to the ureters under cystoscopic observation
or (2) by surgical insertion through the abdominal wall
into the ureters.