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Flashcards in Chapter 5- PharChem lec Deck (76):
1

To inactivate the proteolytic enzyme, pepsin

Antacid

2

General inflammation of the gastric mucosa

Gastritis

3

A specified curcumscribed erosion

Peptic ulcer

4

Occurs when the esoohageal sphincter is defective: lower end of the esophagus

Esophageal ulcer

5

Malignancy and hemorrhage: stomach

Gastric ulcers

6

Perforation: duodenum

Duodenal ulcers

7

Its main function is to react with acid (citric, tartaric etc.)

Sodium bicarbonate

8

White, viscous suspension permitted to contain aromatics

Aluminum hydroxide gel

9

White, colorless, tasteless, amorphous powder

Dried aluminum hydroxide gel

10

Treatment of hyperchlorhydria, peptic ulcer and intestinal toxemia

Aluminum hydroxide gel

11

Tend to be constipating and are usually found in combination with magnesium antacids

Calcium-containing antacids

12

Synonym of calcium carbonate

Precipitated chalk

13

Synonyms of tribasic calcium phosphate

Precipitated calcium phosphate, tertiary calcium phosphate, calcium phosphate

14

White, colorless and tasteless powder used in the treatment of hyperacidity. No gas produced that may cause flatulence

Tribasic calcium phosphate

15

Synonyms of magnesium carbonate

Carbonate of magnesia, magnesium carbonate, heavy magnesium carbonate

16

White, bulky, odorless powder having a slightly earthly taste

Magnesium carbonate

17

White, bulky powder. Used as laxative in high doses.

Magnesium hydroxide

18

Minimize the interaction of glass containers and MgOH2

Milk of magnesia

19

Synonym of Magnesium oxide

Magnesia

20

Occupy a volume of approximately 40 to 50 mL

Light magnesium oxide

21

Occupy a volume of approximately 10 to 20 mL

Heavy magnesium oxide

22

May be employed as a laxative diuretic and antacid. Also given as arsenic antidote

Magnesia

23

Compound of magnesium oxide and silicon dioxide containing varying proportions of water

Magnesium trisilicate

24

Fine, white, odorless, tasteless powder, free from grittiness

Magnesium trisilicate

25

Gastric antacid especially valuable on peptic ulcer

Magnesium trisilicate

26

Synonym of magnesium phosphate

Tertiary magnesium phosphate

27

White, odorless snd tasteless powder used as an antacid

Magnesium phosphate

28

No single antacid meets all the criteria of an ideal antacid

Combination antacid preparations

29

Aluminum hydroxide gel - magnesium hydroxide

Aludrox
WinGel
Maalox
Cremalin

30

Aluminum hydrocide gel -magnesium trisilicate

Gelusil
Tricreamalate
Triosgel

31

Chemical combination if aluminum hydroxide and magnesium hydroxide (Riopan)

Magaldrate

32

Containing antacids : Di-Gel, Mylanta
Complain of being gassy

Simethicone

33

Sodium bicarbonate containing antacids: Gaviaon, Foamtab
Provides a symptomatic relief of reflux esophagitis

Alginic acid

34

Commonly used forbthe treatment if diarrhea

Protectives and adsorbents

35

Can be caused by bacterial toxins, chemical poisons, drug, allergy and disease

Acute diarrhea

36

Can result from gastrointestinal surgery, carcinomas, chronic inflammatory conditions and carious adsorptive defects

Chronic diarrhea

37

Should act directly on the smooth muscle of the gut to produce spasm-like effect which decreases peristalsis and increases segmentation

Ideal antidiarrheal

38

Are only imeffective if there is an actual infection caused by microorganism

Antibacterial

39

Supposedly adsorb tocins, bacteria and viruses along with providing a protective coating if the intestinal mucosa

Adsorbent-protective

40

Exerts a mild astringent and antiseptic action

Soluble bismuth cation

41

Incompatible with tragacanth. Effective nin-irritant intestinal antiseptic

Busmuth subnitrate

42

Synonyms of bismuth subnitrate

Basic bismuth nitrate, white bismuth

43

Synonym of bismuth subcarbonate

Basic bismuth carbonate

44

Protective and antacid effect in inflammations of the stomach and bowels

Bismuth subcarbonate

45

Synonyms of milf of bismuth

Bismuth magma, bismuth cream

46

Contains bismuth hydroxide and bismuth subcarbonate in suspension in water. Astringent and antacid

Milk of bismuth

47

Synonyms of kaolin

Porcelain clay, china clay, bolus alba

48

Native hydrated aluminum silicate, powdered and freed from gritty particles by elutriation

Kaolin

49

Found together with the vegetable carbohydrate: pectin (kaopectate, Kao-Con) and employed as a pritective and adaorbent in diarrheal disorders

Kaolin

50

Neutralize excess HCl which maybe causing pain and possible ulceration

Antacids

51

Adsorbent in the treatment of diarrhea and an antidote in certain types of poisoning

Activated charcoal

52

Agents that quicken and increase evacuation from the bowels

Saline cathartics (purgatives)

53

Are mild cathartics

Laxatives

54

Act by local irritation on the intestinal tract, which increases peristaltic activity

Stimulant laxatives

55

Made from cellulose and other non-digestible polysaccharides which swell when wet and with the increased bulk stimulates peristalsis

Bulk-forming laxatives

56

Act neither as lubricants facilitating the passage of compacted fecal material or as stool softeners

Emolient laxatives

57

Act by increasing the osmotic load of the gastrointestinal tract

Saline cathartics

58

Poorly adsorbed anions that are used as saline cathartics

Biphosphate, phosphate, sulfate and tartrate

59

Synonyms of monobasic sodium phosphate

Sodium dihydrogen phosphate, sodium acid phosphate, primary sodium phosphate, sodium biphosphate

60

Urinary acidifier, cathartic, used to render urine acidic in case of cystitis with hexamethylenetetramine (methenamine)

Monobasic sodium phosphate

61

Synonyms of dibasic sodium phosphate

Disodium hydrogen phosphate, secondary sodium phosphate

62

Colorless or white granular salt

Dibasic sodium phosphate

63

Synonyms of potassium tartrate

Rochelle salt, seignette salt

64

Cathartic. Mild laxative to more potent hydragogue depending upon the dose administered

Rochelle salt

65

Form in which potassium sodium tartrate is administered as cathartic

Seidlitz powder

66

Alkaline cupric tartrate

Fehling's solution

67

Synonyms of magnesium sulfate

Epsom salt, bitter salt

68

Small, colorless crystals, usually needle-like, with cooling saline bitter taste

Magnesium sulfate

69

Active cathartic operating with but little pain or nausea and producing watery stools

Magnesium sulfate

70

Used as an anticonvulsant (parenterally)

Magnesium sulfate

71

Synonym of magnesium citrate

Citrate of magnesia, purgative lemonade

72

Made by reacting magnesium carbonate with citric acid. Must be sterilized or pasteurized

Magnesium citrate

73

Sodium sulfate

Glauber's salt

74

Potassium phosphate

Dibasic potassium phosphate, dipotassium hydrogen phosphate, DKP

75

Potassium bitartrate

Cream of tartar, potassium acid tartrate, potassium hydrogen tartrate

76

Calomel

Mercurous chloride, mild mercury chloride