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Flashcards in Chapter 6 and 7 Deck (27)
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1

What is the most common form of hyperthyroidism?

Grave>s disease

2

How do Ca+ molecules enter the cell?
3 ways

through voltage-gated calcium channels
or
ligand
or
mechanically gated

3

To what Ca can bind in the cell?
2

Calmodulin
Other Ca2+ binding proteins

4

PLC converts membrane phospholipids into?

DAG + IP3

5

What DAG does?

activates PK-C which phosphorylates proteins

6

What IP3 does?

It causes the release of Ca2+ from organelles,
creating a Ca 2+ signal
slide 23

7

The receptor-channel can be activated by 2 things:

GPCR or when a ligand binds to it

8

What PK-C do?

it phosphorylates proteins

9

What is the signal pathway for Na-K pump?

Receptor-channel

10

GPCR binds to which nucleotide

guanosine

11

What is the signal pathway for insulin?

tyrosine kinase

12

The ___system is wired?

Nervous
its cell-to cell
slide 30

13

Ant pit secretes

1- TSH
2-ACTH
3- GH
4- FSH
5-PRL
6- MSH

14

Post pit secretes

ADH
Oxytocin

15

2 anterior pituirary hormones that have and hypothalamic inhibiting hormone?

PRL : inhibited by PIH (dopamine)
GH, somatotropin : inhibited by SS aka GHIH

16

Which hormone has a nonendocrine target ?

PRL

17

describe synergism

1+1 >2

18

describe permissiveness

2+0=0

19

Peptide H are made as inactive :

Preprohormones and they are processed to prohormones in the ER.

20

Endocrine cell secrete ...

hormones

21

Exocrine cell secrete ...

products

22

Iodine is essential for the production of...
Lack of iodine can cause ... in adult

Thyroxine
goitre

23

In children, when iodine is lacking or deficient, it can cause...

retard of growth and development
= cretinism

24

TSH stimulates thyroid cells to produce...

T4 (thyroxine)
+
T3 (triiodothyronine)

25

Adrenal cortex is stimulated by the hormone ___
and adrenal cortex secretes ____

ACTH (adrenocorticotropic hormone)
cortisol

26

GH stimulates ...

growth and metabolic effects

27

Pineal gland produces...

Melatonin