Chapter 7 Flashcards
(10 cards)
types of chemical communication
paracrine
endocrine
synaptic
paracrine signaling
acts over a longer range and involves the secretion of chemical signals onto nearby groups of target cells
endocrine signaling
secretion of hormones into the blood stream where they can affect targets throughout the body
3 components of chemical signaling
signal, ex: NT
receptor: NT receptors
effector: ion channel
classes of cell signaling molecules
cell impermeant
cell permeant
cell associated molecules
cell impermeant
cannot pass the plasma membrane
need to bind to the extracellular portion of the plasma membrane receptor proteins
cell permeant
can cross the membrane and act directly on receptors inside cells
cell associated signaling molecules
act only on cells they are physically in contact with that carry a specific signal
what determines the cellular response?
receptors
intracellular receptors
activate signal cascades
are activated by cell permeant molecules