Chapter 8 - Anti-infective Agents Flashcards Preview

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Flashcards in Chapter 8 - Anti-infective Agents Deck (15):
1

What is the goal of the treatment

Interfere with normal functioning of the invading organism to prevent from reproducing and causes cell death without affecting the host cell.

2

What statuses should you worry about with a child taking antibiotics

Nutritional status and hydration

3

Are antibiotics safe for pregnancy and lactation?

No.
Cross breast milk and placenta leading to go is affects in the fetus.

4

What statuses do you assess with an older patient taking antibiotics
List 6

Hepatic, gi, renal, neuro, nutritional status and hydration.

5

Which drug prevents the cells of the invading organism from using substances essential to growth and reproduction

Sulfonamides and mycobacterials

6

What drugs interfere with the steps involved in protein synthesis?

Aminoglycosides and macrolides

7

Interfere with dna synthesis of the cell, inability to divide and reproduce.

Floroquinolones

8

Producing an enzyme inactivating the drug
Altering permeability of the cell
Altering binding sites
Producing a chemical antagonist

Are an example of what?

Acquired resistance

9

What develops resistance through actual genetic mutation

Microbes

10

Do anti-infectives invade the host.

Yes, there has been no anti infective drug that has been developed that doesn't affect the host.

11

Which drug is used to treat malaria and rheumatoid disease?

Chloroquine

12

What is something to re beer about the effects of cholooquine

Accumulate in the retina and optic nerve and cause blindness

13

Pseudomonas and proteus superinfection are associated with which spectrum of antibiotic

Broad spectrum

14

Which drug accumulates in the 8th cranial nerve causing hearing loss, vertigo, and dizziness

Aminoglycosides

15

Which gram stain is associated with gi and gu infections

Negative