Chemistry of Heart Flashcards Preview

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Flashcards in Chemistry of Heart Deck (51):
1

Risk factor of heart disease: Family history

Wirst ear
Balness
APOE4 Gene (high cholesterol accumulation)

2

DIabetes:
1. oral glucose tolerance
2. Fasting blood glucose

1. > 11
2. >7

3

Cholesterol risk factor

APOE4 Gene (high cholesterol accumulation)

4

Homocysteine

is NOT a risk factor

5

Inflammation signs

Heat, pain, redness & swelling

6

C-Reactive Protein (CRP)

identification of Inflammation.

7

Increase level of CRP =

Risk of heart attack and cancer.

8

High level of CRP > 100mg/L

More likely bacterial than viral infection

9

Blood Pressure=

Systolic/ Diastolic

10

Systolic

Heart pump out blood

11

Diastolic

Heart is resting in between pumping (blood flow back into the heart

12

To reduce heart risk

4-5 times/week exercises
Low fat, more multigrain
Patassium
lower salt consumption (max: 2300mg)

13

Optimal NACL

1500mg

14

Dr. James DiNicolantonio claim

should take high dose of salt, bc low NACL diets decrease memory and increase sugar blood level.

15

Diuretics

increase excretion kidney (first drugs try)

16

Angiotensin Convertor Enzyme (ACE) inhibitors

Block angiotensin II

17

Role of angiotensin II

control BP to not drop to much in the smooth tissues

18

Beta-Blocker

Block adrenalin
decrease HR and force of contraction of the heart

19

Calcium Channel Blockers

Dilate arteries and decrease force of contraction of the heart

20

When fibrous plaques is formed it creates

blood clot formation bc body perceive it as a problem.

21

Angina pectoris 2 types:

1. Exercises induced
2. Vasoplastic unstable (at rest)--> spasm

22

Nitroglycerine

take place of the adrenaline receptor

23

Nitroglycerine side effect

fatigue

24

Arginine

Stop platelet to form (not conclusive research about it)

25

COEnzyme Q10

Is essential to synthesize ATP
Prescribe in China/Japan
Level reduce in heart of congestive heart failure patient so increase the level

26

Arythmia rx

Sotalol
Amiodarone

27

Myocardial infarction indicator (bloodtest)

Troponin
Creatinine Kinase (CK)

28

First heart transplant by

Dr. Chris Barnard

29

Bigger risk factor for heart disease

Smoking

30

T or F: Cholesterol need to be consume because the body do not produce it naturally.

F.

31

Main cause of high cholesterol:

Saturated fats

32

Normal BP

120/80

33

cut off for hypertension

135/90 (need more than one measurement)

34

2 types of hypertension:

Mental stress-caused
Essential hypertension (cause unknown)

35

Bad marriage induce change on the BP:

the increase of 6mmHg

36

Arginine promote the formation of

Nitric Oxide (only neurotransmitters in gas form)

37

Dropsy mean

bloatedness (retention of liquids)--> oedema

38

Digitalis reffers to

as cardiac glycosides

39

Thrombolytics use is

Tissue Plasminogen Activator

40

Which protein is responsable to dissolve clot

Plasmin

41

NNT (Number Needed to Treat)

Best measure for efficacy of the drugs (how much person need to be treat before having one positive respond)

42

Statin NNT

150

43

Vit B deficiency lead to

Increase level of homocysteine

44

Statin act as

lowering level of cholesterol
decrease inflammation

45

Potassium ideal daily intake:

4500mg

46

Vasotec is

ACE inhibitor

47

Inderal is

beta-blocker

48

Adalat is

Calcium channel blocker

49

Sotacor is

anti-arythmic

50

Amiodarone is

anti-arythmic

51

Sirolimus is

reduce inflammation in the stent applicance