CHEMOTHERAPEUTIC DRUGS - ANTIVIRAL AGENTS. AGENTS FOR CHEMOTHERAPY OF CANCER Flashcards Preview

Pharmacology > CHEMOTHERAPEUTIC DRUGS - ANTIVIRAL AGENTS. AGENTS FOR CHEMOTHERAPY OF CANCER > Flashcards

Flashcards in CHEMOTHERAPEUTIC DRUGS - ANTIVIRAL AGENTS. AGENTS FOR CHEMOTHERAPY OF CANCER Deck (45):
1

The following antiviral drugs are the analogs of nucleosides

Saquinavir

2

The drug, a derivative of adamantane

Rimantadine

3

The drug, a derivative of pyrophosphate

Foscarnet

4

The drug, inhibiting viral DNA synthesis

Acyclovir

5

The drug, inhibiting uncoating of the viral RNA

Rimantadine

6

The drug, inhibiting viral reverse transcriptase

Zidovudine

7

The drug, inhibiting viral proteases

Saquinavir

8

The drug of choice for herpes and cytomegalovirus infection treatment

Acyclovir

9

The drug which belongs to nonnucleoside reverse transcriptase inhibitors

Nevirapine

10

The following antiviral drugs are antiretroviral agents

- Zidovudine
- Zalcitabine
- Didanozine

11

The drug used for influenza A prevention

Rimantadine

12

The drug used for HIV infection treatment, a derivative of nucleosides

Zidovudine

13

The antiviral drug which belongs to endogenous proteins

Interferon alfa

14

The drug which belongs to nucleoside reverse transcriptase inhibitors

Didanosine

15

The following antiviral drugs are anti-influenza agents

- Amantadine
- Interferons
- Rimantadine

16

The unwanted effects of zidovudine

Anemia, neutropenia, nausea, insomnia

17

The unwanted effects of intravenous acyclovir infusion

Renal insufficiency, tremors, delerium

18

The drug that can induce peripheral neuropathy and oral ulceration

Zalcitabine

19

The unwanted effects of didanozine

Peripheral neuropathy, pancreatitis, diarrhea, hyperuricemia

20

The unwanted effects of indinavir

Nephrolithiasis, nausea, hepatotoxicity

21

The drug that can induce nausea, diarrhea, abdominal pain and rhinitis

Saquinavir

22

The following effects are disadvantages of anticancer drugs

- Low selectivity to cancer cells
- Depression of bone marrow
- Depression of immune system

23

Rational combination of anticancer drugs is used to

Provide synergism resulting from the use of anticancer drugs with different mechanisms combination

24

The anticancer alkylating drug, a derivative of chloroethylamine

Cyclophosphamide

25

The anticancer alkylating drug, a derivative of ethylenimine

Thiotepa

26

The group of hormonal drugs used for cancer treatment

Glucocorticoids and gonadal hormones

27

The anticancer alkylating drug, a derivative of alkylsulfonate

Busulfan

28

The anticancer drug of plant origin

Vincristine

29

Action mechanism of alkylating agents is

Producing carbonium ions altering DNA structure

30

The anticancer drug, a pyrimidine antagonist

Fluorouracil

31

Methotrexate is

A folic acid antagonist

32

The antibiotic for cancer chemotherapy

Doxorubicin

33

Fluorouracil belongs to

Antimetabolites

34

The action mechanism of anticancer drugs belonging to plant alkaloids

Mitotic arrest at a metaphase

35

General contraindications for anticancer drugs are

- Depression of bone marrow
- Acute infections
- Severe hepatic and/or renal insufficiency

36

Action mechanism of methotrexate is

Inhibition of dihydrofolate reductase

37

The anticancer drug belonging to inorganic metal complexes

Cisplatin

38

The indication for estrogens in oncological practice

Cancer of prostate

39

Enzyme drug used for acute leukemia treatment

Dihydrofolate reductase

40

The following drugs are derivatives of nitrosoureas

- Carmustine
- Lomustine
- Semustine

41

The group of drugs used as subsidiary medicines in cancer treatment

- Cytoprotectors
- Bone marrow growth factors
- Antimetastatic agents

42

Estrogen inhibitor

Tamoxifen

43

Antiandrogen drug

Flutamide

44

The drug belonging to aromatase inhibitors

Anastrozole

45

The drug belonging to gonadotropin-releasing hormone agonists

Leuprolide

Decks in Pharmacology Class (41):