Chemotherapy and Radiotherapy in Gynaecalogical Cancers Flashcards Preview

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Flashcards in Chemotherapy and Radiotherapy in Gynaecalogical Cancers Deck (17):
1

A women presents with early satiety, abdominal distension and pain. How long and how often would these symptoms have to had been occuring for in order for a diagnosis of ovarian cancer to be considered?

Less than 12 months duration more than 12 times a month

2

What would be classed a suspicious findings on ovarian US?

Multilocular cyst
Solid areas
Bilateral lesions
Ascites
Intra abdominal metastases

3

What is the % 5 year survival for a women with stage 1 ovarian cancer?

80 - 90%

4

What is the % 5 year survival for a women with stage 2 ovarian cancer?

65%

5

What is the % 5 year survival for a women with stage 3 ovarian cancer?

15 - 35%

6

What is the % 5 year survival for a women with stage 4 ovarian cancer?

Up to 15%

7

What is the first line chemotheraputic agent given in ovarian cancer when there is curative intent?

Paclitaxel

8

What is the first line chemotheraputic agent in advanced ovarian cancer?

Carboplatin

9

What % of ovarian tumours respond to tamoxifen?

10%

10

How is ovarian cancer staged?

Midline laporotomy with assessment of the peritoneal surface.
Total abdominal hysterectomy, bilateral salpingoophrectomy and infracolic omentectomy with retroperitoneal lymph node assessment.
Close inspection of the liver, spleen, peritoneum etc

11

Discuss the surgery is early ovarian cancer

Debulking surgery
Peritoneal cytology, hysterectomy, removal of the ovaries and fallopian tubes and infracolic omentectomy

12

What is the current chemotherapy regime in ovarian cancer?

Carboplatin and Paclitaxel given for 6 cycles at three weekly intervals.

13

A women undergoing chemotherapy for ovarian cancer loses her hair. Which drug will be causing this?

Paclitaxel. Carboplatin doesn't cause alopecia.

14

Which chemotheraputic agent, used in ovarian cancer, causes peripheral sensory neuropathy?

Paclitaxel

15

Which chemotheraputic agent, used in ovarian cancer, causes joint pain? When does this usually occur?

Paclitaxel. 3 days after treatment

16

What would you think if you saw signet ring cells on histology of an ovarian tumour?

Secondary metasates from a gastric tumour.

17

What are the most common chemotheraputic agents used in endometrial cancer?

Cisplatin
Doxorubin