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HEMATOLOGIE > Chimiotherapie > Flashcards

Chimiotherapie Flashcards

1
Q

Toxicité vincristine ? (2)
(alcaloïde extrait pervenche Madagascar)

= inh polymérisation microtubules, arrêt mitose

A

Neuropathie périphérique

Constipation

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2
Q

Toxicité antracycline (-rubicine) ? (2)

= intercalant (paire azoté ADN), inh topo II

A

Toxicité cutanée si extravasation

Toxicité cardiaque

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3
Q

Toxicité aracytine? (3)

= anti métabolite

A

Fièvre
Toxicité cutanée
Toxicité cérébelleuse

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4
Q

Toxicité cyclophosphamide ? (2)

= agent alkylant

A

Cystite hémorragique

Cancer vessie

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5
Q

Toxicité asparaginase? (3)

= cytostatique (rend impossible blaste sur produire propre asparagine)

A

Toxicité hépatique
Pancréatite
Risque de thrombophlébite

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6
Q

Toxicité methotrexate ? (3)

= anti métabolite, inh dihydrofolate reductase

A

Fibrose hépatique
Fibrose pulmonaire
Nephrotoxique

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HEMATOLOGIE (5 decks)

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