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Flashcards in Cholinergic Drugs Deck (15)
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1

Cholinergic Drugs

Parasympathetic Nervous system mimic the effect of acetylcholine.

2

Cholinestrase

The enzyme responsible for breaking down ACh

3

Muscarinic

Receptors located postsynaptically in the effector organs supplied by the parasympathetic fibers

4

Direct acting

bind to cholinergic receptors and activate them

5

Indirect acting

make more ACh avaliable at the receptor site allowing ACh to bind to and stimulate the receptor

6

Atropine

antidote for cholinergic drugs

7

Acetocholine (ACh)

the neurotransmitter responsible for the transmission of nerve impulses to the effector cells in the parasympathetic nervous system.

8

The desired effects of cholinergic drugs come from the stimulation of what receptors?

Muscarinic receptors

9

The undesired effects of cholinergic drugs come from what recptors?

Nicotinic

10

Bethanechol is used for the treatment of which condition?

Urnary retention

11

When caring for a patient with myasthenia gravis the nurse can expect to see which drug ordered for the symptomatic treatment of this disease?

Pyridostigmine (Mestinon)- this drug increases muscle strength and causes reversal of nondepolarizing neuromuscular blocking agents. Inhibits breakdown of ACh and prolongs its effects.

12

cholinergic crisis

Severe muscle weakness and resipratory paralysis due to excessine ACh. often seen with Myasthenia gravis as an adverse effect of drugs used to treat the disease,

13

Myasthenia Gravis

Myasthenia gravis is either an autoimmune or congenital neuromuscular disease that leads to fluctuating muscle weakness and fatigue

14

A patient has recieved an inadvertent overdose of a cholinergic drug. The nurse will monitor for early signs of a cholinerigic crisis?

Salivation, flushing of the skin, Abdominal cramps and dyspenea

15

The nurse will expect to give what drug to a patient who is experiencing a cholinergic crisis?

Atropine