Chromosome swapping questions Flashcards
1
Q
Chronic myelgenous leukemia is a result of what sort of swap?
A
c-able on 9 transfered to 22 increasing production “Philly chromosome”
Treat with imatinab
2
Q
What swap is seen in Burkits lymphoma?
A
8-14
Transfer of the C-Myc gene
3
Q
What is seen in a B- cell follicular lymphoma transfer?
A
transfer of BCL-2 gene from 14 to 18 preventing apoptosis by stopping the leakage of cytochrome c.
