Flashcards in Chronic & Acute Renal Failure Deck (59)
Loading flashcards...
1
Do you need ARF to get CRF?
Nope
2
if you have CRF does that mean you had to have ARF?
Nope
3
Renal failure is defined as failure of what?
filtration
4
ARF reversible?
yes the sooner you treat it the better the outcome
5
definition of renal failure is how much urine flow per day?
less than 500ml/day
6
CRF timeline? reversible?
develops over 6 months-years
irreversible
7
What is normal GFR /min? /day?
125ml/min
180ml/day
8
GFR at 65? at 80?
65: 100ml/min 144L/day
80: 75ml/min 108L/day
9
What is considered significant CRF ____ml/min?
<72L per day
10
loss of GFR is coupled with loss of?
tubular reabsorption/secretion
11
When do you get endocrine impairment with renal failure?
more so CRF
12
3 main endocrine impairment with renal failure?
RAS: +++vasocontriction
impaired vitamin D activation
decreased erythropoeitin - anaemia
13
plasma urea for GFR assessment?
NOPE. crap
14
what is normal creatinine levels?
50-120uM/L
15
equation for creatinine clearance?
UV/P = GFR
16
Normal hydrostatic pressure in glomerulus is?
55mmHg
17
when do you no longer filter anything in glomerulus?
<40-45mmHg
18
ARF: What's more common? oliguria? Anuria?
oliguria
19
ARF: GFR falls how?
acutely hours/days
20
3 areas of acute renal failure?
pre-renal
renal
post-renal
21
what is ATN?
acute tubular necrosis
22
in pre-renal ARF: what would systemic and Glomerulous pressures be less than?
systemic: <45mmHG
23
causes of pre-renal ARF? 5 big ones
Shock
Sepsis
Haemolysis
rhabdomyolysis
nephrotoxic drugs
24
3 big causes of renal/intrinsic ARF?
glomerular disease
interstitial nephritis
tubular damage
25
what can cause glomerular disease?
IgA immune complexes post group A strep infections
26
interstitial nephritis often related to?
drugs
27
3 Toxins that can cause tubular damage in ARF?
antibiotics
contrast media
myo/haemoglobin
28
2 ischemic events that cause tubular damage in ARF? which one is most common?
ATN (most common)
vascular obstruction
29
how does ATN cause death?
Acidosis, increase in K+ levels: arrythmias
30
