Chronic Liver Disease Flashcards Preview

Abdo > Chronic Liver Disease > Flashcards

Flashcards in Chronic Liver Disease Deck (24):
1

What are the clinical features of chronic liver disease ?

A-J: Ascites(abdominal distention) and anaemia, Bruising, Clubbing and change in nail colour:leukonychia and terry's nails, Dupuytren.s contracture, Encephalopathy, palmar erythema and parotid enlargement, F for spider naevi, Gynaecomastia and xanthelasma, Hair loss and hepatomegaly, I ? and Jaundice

2

Describe how you would elicit a history for chronic liver disease (6)

1.

3

Are cirrhosis and chronic liver disease the same thing ?

Cirrhosis and chronic liver disease(CLD) are not the same thing

4

What is cirrhosis?

is the pathological process of chronic hepatocyte necrosis, fibrosis and regeneration nodules and intermixed with this CLD

5

State 4 clinical features of cirrhosis

1,

6

In relation to cirrhosis describe:
Hypoproteinaemia 😭

Damage to the hepatocyte leads to a decrease in albumin synthesis

7

in relation to cirrhosis describe:
Abnormal clotting

The Liver

8

In relation to cirrhosis describe:
Secondary hyperaldosteronism

The Liver

9

in relation to cirrhosis describe:
Portal hypertension

Damage to the liver architecture results in backflow of blood through the portal vein causing portal hypertension

10

State the 3 main clinical features that both cirrhosis and portal hypertension share

oesophageal varices, ascites and hepatic encephalopathy

11

Describe oesophageal varices in relation to cirrhosis and portal hypertension 😭

oesophageal varices are dilated veins in the oesophagus that can rupture and lead to bleeding. It is a common cause of a upper GI bleed

12

Describe ascites in relation to cirrhosis and portal hypertension
😭

Ascites is the accumulation of fluid in the peritoneal cavity, leading to abdominal distention. This can occur due to the following 3: 1. postural hypotension (increase in hydrostatic pressure), 2. secondary hyperaldosteronism: increase in salt and water retention, 3. hypoproteinemia:decrease in oncotic pressure

13

Describe hepatic encephalopathy in relation to cirrhosis and portal hypertension 😭

Hepatic encephalopathy is failure of the liver to eliminate nitrogenous waste produced by gut bacteria, leading to cerebral oedema when the astrocytes try to clear it away

14

Describe the signs/symptoms of hepatic encephalopathy in relation to cirrhosis ? 😭

impaired cognitive function: 2Cs and 2S
confusion and drowsiness
coma
stupor
sleep disturbance and restlessness

15

What bedside investigations would you do for cirrhosis ?

History and examination

16

Describe what you see on a FBC for cirrhosis 😭

Decrease in WCC and platelet due to hypersplenism or splenomegaly

17

Describe what you will see on LFTS initially for cirrhosis

d

18

Describe what you will see on LFTS in the final stages for cirrhosis

h

19

State the 2 basic imaging for cirrhosis

f

20

Describe what 6 things you could see on a liver USS+ duplex scan

1.

21

Describe the use of a Liver biopsy in cirrhosis

To establish clinical diagnosis

22

State the 2 advanced imaging tests you would do for cirrhosis

Ascities tap and MRI and MRI scoring systems

23

What is the use of the ascities tap in cirrhosis ?

Urgent MC and S

24

What is the use of MRI and MRI scoring systems in

Quantify severity of liver cirrhosis