class 9: molecular genetics III Flashcards Preview

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Flashcards in class 9: molecular genetics III Deck (17):
1

synthesis aka

replication

2

semi conservativ

each preexisting strand serves as template for replication and each new DNA molecule is composed of one original template and one newly created strand built upon by template strand

3

gene

unit of info encoded in particular sequence of nucleotides

4

point mutation

simplest form of mutation, change in a single nucleotide within a gene

5

substitutions

single nucleotide replace by diff nucleotide

6

silent muation

one that has no effect on protein bieng produce proimarily bc redundacy of genetic code- falls under substitutions

7

missense mutation

altered codon still codes for amino acid, now for a diff amino acid than was originally coded for can produce slightly alterned function, different proteins

8

nonsense mutation

mtutation changing codon for an amino acid into one of three stop codons, incomplete, unlikely to produce funcitoning protein

9

insertion and deletions

single nucleotides or longer stretches of nucelotides insert or delete in gnee- short or lengthen entire gene sequenec, can change entire reading frame of gene

10

frameshift mutations

change how gene is read (groups of three)

11

duplication

delteion gets added onto same place on other member of homologous pair

12

inversion

deletion becomes reattached to original choromosome, but in opposet direction

13

translocation

broken off fragment inserted into non homologous chromose

14

aneuploidy

number of choromsomes in a cell can change resulting in a mutated condition

15

nondisjunction

sister chromatids may not separate during mitosis or meiosis II- one daughter cell too many copies of one chromosome, other has to few

16

germ line cell

cells that undergo meiosis to producegaemetes

17

mutagens

environemntal agents

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