Classic Presentations - Clinical Presentation//Diagnosis/Disease Flashcards Preview

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Flashcards in Classic Presentations - Clinical Presentation//Diagnosis/Disease Deck (26):
1

Abdominal pain, ascites, hepatomegaly

Budd-Chiari syndrome (post-hepatic venus thrombosis)

2

Achilles tendon xanthoma

Familial hypercholesterolemia (dec. LDL receptor signalling)

3

Cold intolerance

Hypothyroidism

4

Conjugate lateral gaze palsy, horizontal diplopia

Internuclear opthalmoplegia (damage to MLF; bilateral [MS], unilateral [stroke])

5

Chorea, dementia, caudate degeneration

Huntington disease (autosomal dominant CAG repeat expansion)

6

"Butterfly" facial rash and Raynaud phenomenon in a young female

Systemic lupus erythmatosus

7

Blue sclera

Osteogenesis imperfecta (type I collagen defect)

8

Hyperphagia, hypersexuality, hyperorality, hyperdocility

Kluver-Bucy syndrome (bilateral amygdala lesion)

9

Hyperreflexia, hypertonia, Babinski sign present

UMN damage

10

Hyporeflexia, hypotonia, atrophy, fasciculations

LMN damage

11

Dry eyes, dry mouth, arthritis

Sjogren syndrome (autoimmune destruction of exocrine glands)

12

Dark purple skin/mouth nodules in a patient with AIDS

Kaposi sarcoma, associated with HHV-8

13

Resting tremor, rigidity, akinesia, postural instability

Parkinson disease (nigrostriatal dopamine depletion)

14

Small, irregular red spots on buccal/lingual mucosa with blue-white centers

Koplik spots (measles; rubeola virus)

15

Systolic ejection murmur (crescendo-decrescendo)

Aortic valve stenosis

16

"Worst headache of my life"

Subarachnoid hemorrhage

17

Toe extension/fanning upon plantar scrape

Babinski sign (UMN lesion)

18

Unilateral facial drooping involving forehead

Facial nerve (LMN CN VII palsy)

19

Red "currant jelly" sputum in alcoholic or diabetic patients

Klebsiella pneumoniae

20

Ptosis, miosis, anhydrosis

Horner syndrome (sympathetic chain lesion)

21

Pupils accommodate but don't react to light

Argyll Robertson pupil (neurosyphilis)

22

Rapidly progressive leg weakness that ascends, following GI/upper respiratory infection

Guillan-Barre syndrome (acute autoimmune inflammatory demyelinating polyneuropathy)

23

Rash on palms and soles

Coxsackie A
Secondary syphilis
Rocky Mountain spotted fever

24

Recurrent colds, unusual eczema, high serum IgE

Hyper IgE syndrome (Job syndrome: neutrophil chemotaxis abnormality)

25

Dysphagia (esophageal webs), glossitis, iron deficiency anemia

Plummer-Vinson syndrome (may progress to esophageal squamous cell carcinoma)

26

Elastic skin, hypermobility of joints

Ehlers-Danlos syndrome (type III collagen defect)