clindamycin & metronidazole Flashcards Preview

Z A Pharm III > clindamycin & metronidazole > Flashcards

Flashcards in clindamycin & metronidazole Deck (10):
1

What is MOA clindamycin

inhibit protein synthesis (50S)

2

What does clindamycin treat

anaerobes
Paracites
PCP

3

How is clindamycin eliminated

bile

4

What are common uses for clindamycin

anaerobic infections
acne
gardnerella vaginalis

5

What are adverse effects of clindamycin

Diarrhea
hypersensitive
hepatic toxicity
pseudomembranous colitis

6

what is MOA metronidazole

reactive metabolites that damage DNA

7

What does clindamycin treat

G - anaerobes
G+ anaerobes
H pylori
protozoa

8

What are common uses of metronidazole

DOC - C difficile colitis
peptic ulcer
vaginosis
chrohns

9

What are types of metronidazole

Flagyl IV
- 15 over hr, then 7.5 over 1 hour q6h

10

What are adverse effects of metronidazole

Neurologic effects
disulfiram w/ alcohol
GI upset
warfarin
hypersensitive