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Neurology Clerkship > Clinical Neuroscience > Flashcards

Clinical Neuroscience Flashcards

1
Q

What are the components of the BBB?

A
  • endothelial cells with tight junctions
  • astrocyte foot processes
  • basement membrane
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2
Q

Which structures lack a BBB?

A
  • area postrema
  • median eminence of the hypothalamus
  • neurohypophysis
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3
Q

What is Dales principle?

A

A given neuron only releases one type of NT and its effect on the post-synaptic terminal is the same across all connections (acetylcholine released and causes excitation to all terminal neurons that have connections)

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4
Q

How is acetylcholine synthesized?

A

acetyl coenzyme A + choline –> acetylcholine by choline acetyltransferase

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5
Q

How is glutamate synthesized?

A

transamination of alpha-ketoglutarate

glutamine to glutamate by enzyme glutaminase

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6
Q

how is GABA synthesized?

A

synthesized from glutamate via enzyme glutamic acid decarboxylase (GAD)

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Neurology Clerkship (6 decks)

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