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Flashcards in clinical overview of hypothalamus and pituitary Deck (18):
1

what are hypothalamus and pituitary disorders due to?

hypersecretion, deficiency, hormone resistance

2

what is the cushing syndrome hormone level throughout the day?

increased midnight cortisol compared to normal but normal in mornings

3

hormone hypersecretion and deficiency is due to what?

neoplastic, autoimmune, latrogenic, infectious/inflammatory rxn

4

what are the hormones released by the anterior pituitary gland

prolactin
growth hormone
thyroid stimulating horsmone (TSH)
Follicle stimulating hormone (FSH)
ACTH
luteinizing hormone (LH)

5

what is the mechanism of the anterior pituitary release its hormone?

through blood circulation

6

What hormones are produced in the posterior pituitary

ADH, oxytocin

7

what is the mechanism for the posterior pituitary gland to deliver their hormones

nervous system

8

Hyperprolactinemia

most common benign neoplasm--50% of all functioning pituitary tumors are hyperprolactinemia

Female: amenorrhea, galactorrhea, infertility mild hirtuism

Male:
- diminished libido, visual loss, headache, gynecomastia

9

Addison's Disease

ACTH deficiency: autoimmune disorder directly affecting adrenal gland and start producing less cortisol, therefore feedbacks to pituitary to make more ACTH

Primary adrenal insufficiency: fatigure, weakness, anorexia, nausea, vomiting, weight loss, low BP, depression, hypoglycemia

10

Tx for addison's disease

glucocorticoid; hydrocortisone or prednisone

11

what is the adolescent form of Acromegaly?

Gigantism

12

What is the common surgery to remove adenoma/ tumors in the pituitary gland?

Transsphenoidal surgery

13

what is the most proper treatment for Acromegaly?

growth hormone antagonist, surgery, somatostatin analogues, radiation

14

what test would you need for patient that has prolactinoma

Serum Prolactin

15

What are the two signals that control release of hormones

Releasing hormone produced by hypothalamus and feedback from target organ

16

Which hormone has greatest levels at onset of sleep at nigh

GH

17

what is one thing you must know when testing for hypothalamus/pituitary disorder

hormonal rhythm

18

which hormone is the the most abundant anterior hormone

GH