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Flashcards in clinical pathology Deck (29):
1

subdivisions of clinical pathology

clinical chem, hematology, immunohematology, microbiology

2

anatomical pathology encompasses:

surgical, cytology, autopsy

3

What does SOAP stand for?

Subjective, Objective, Assessment, Plan

4

values obtained on repetitive measurements (reproducibility)

precision

5

extent to which msmts approach true value

accuracy

6

any data collected may be arranged in ____ distribution

Gaussian

7

inter-individual variability includes:

race, gender, age , body size

8

intra-individual variability includes:

diurnal variations, circadian, menstruation, seasonal, aging

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examples of pre-analytic variability:

food intake, exercise, drug therapy

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examples of analytic variability

inaccuracy, imprecision

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examples of post-analytic variability

transcription errors

12

why physicians order tests
(1st view)

1) confirm clinical impression 2) rule out a possible diagnosis or disease 3) use as therapeutic or management guide 4) use as prognostic guide 5) detect disease (screen)

13

basic reason tests done?

screen, confirm/rule out, management

14

therapeutic drug monitoring is performed __ hours after last dose or just before next dose

5

15

lipids require ____ hr fast

12-16

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specimen needs to be ____ and ___ to be biologically meaningful

representative; homogeneous

17

factors to consider before obtaining specimen?

fasting, position? drug interference? time of collection?

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factors to consider before obtaining specimen

IV infusion, adequate labelling, adequate clinical info, time of collection

19

equation for sensitivity?

TP / (TP + FN) x 100

20

equation for specificity?

TN / (TN + FP) x 100 -->true neg/all subjects free of disease x 100

21

what is predictive value of positive result?

% pos results that are true positives

22

what is predictive value of negative result?

% neg results that are true negatives

23

efficiency equation?

TN + TP / entire population x 100

24

prevalence equation

TP + FN / entire population x 100

25

green top has additive:

heparin

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lavendar top has additive:

EDTA (anticoagulant)

27

frequency of correct result in patient with disease

sensitivity

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frequency of correct result in healthy patient

specificity

29

frequency of disease in target population/ total subjects examined who are diseased

prevalence