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Neurology > CNS Infections > Flashcards

CNS Infections Flashcards

1
Q

What is Meningitis?

A

Inflammation of the pia and arachnoid

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2
Q

What is Encephalitis/cerebritis?

A

Inflammation of the brain parenchyma(infectious/non-infectious)

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3
Q

WHat is the classic triad of Meningitis?

A

Fever, Headache, Stiff neck/nuchal rigidity

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4
Q

What is Kernig Sign?

A

Resistance to passive ext of the knee

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5
Q

What is Brudzinski Sign?

A

Spon flexion of the knees and hips when neck is passively flexed

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6
Q

What are the complications of Bacterial Meningitis?

A 
Seizures
Hydrocephalus 
Infarction 
Abcess
Herniation Syndromes
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7
Q

What are the most common cuses of community acquired Meningitis?

A

Strep Pneumo
Neiserria Meningiditis
Haemophilus Influenza

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8
Q

What are the most common cuses of Meningitis in imm compromised?

A

Lysteria monocytogenes

Staph Aureus

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9
Q

How is Meningitis Diagnosed?

A 
Imaging to precede LP
-new onset seizures
-immcomp
-focal findings
-Dec LOC
Blood Cultures
Lumbar punct
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10
Q

What is the Tx of Bacterial Meningitis?

A

Steroids

Decadron

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11
Q

What are the Traits of Aseptic Meningitis?

A

Acute onset
Meningeal S and S
CSF Abn typical of meningitis
Self limited benign course

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12
Q

What are the most common causes of Viral Meningitis?

A 
Enterovirus
HSV 2
HIV
Arthropod borne virus
Lymphocytic Choriomeningitis
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13
Q

What is the pathogenesis of Herpes Simplex Encephalitis?

A

Transported retrograde up the trigeminal n to TGGanglia

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14
Q

What is the Clinical Presentation of Herpes Simplex Encephalitis?

A

Global: Fever, Headache, change in LOC
Focal: Bizarre Behavior, aphasia, seizure, hemiparesis

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15
Q

What are traits of Herpes Simplex Encephalitis CSF?

A

WBC: 5-500 lymphs
Hemorrhagic
inc protein, dec glucose

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16
Q

What is the Tx of Herpes Simplex Encephalitis?

A

IV Acyclovir

17
Q

WHat are the EARLY clinical manifestations of Lyme Neuroborreliosis?

A

Early: Cranial Neuropathy, facial palsy, lymphocytic meningitis, radiculoneuritis

18
Q

WHat are the LATE clinical manifestations of Lyme Neuroborreliosis?

A

Encephalopathic/encephalomyelitis syndrome
Chronic Lyme disease
Abtx no effect

19
Q

What are common infectious causes of Chronic Meningitis?

A

Mycobacteria
B. Burgdorferi, T pallidum
Cryptococcus, Coccidioides, histoplasma
Taenia Solium, Toxoplasma

20
Q

What are common non- infectious causes of Chronic Meningitis?

A

Neoplastic
Sarcoid
Vasculitis
Chemical

Neurology (9 decks)

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