CNS Stimulant Flashcards Preview

Pass Naplex Now Book II > CNS Stimulant > Flashcards

Flashcards in CNS Stimulant Deck (25):
1

Ritalin IR
Ritalin LA
Methylin
Concerta OROS
Metadate CD

- MOA
- SEs
- DDIs
- DOC
- Indication:
- Other stimulants

Methylphenidate

- Ritalin IR: BID-TID b/4 meal. Max 20mg TID. Rapid abs
- Ritalin LA: Can open n sprinkled on applesauce
- Methylin: chewable tabs n oral sol'n
- Concerta OROS: osmotic system
Come in: 18, 27, 36, 54 mg ER
- Metadate CD: 30% IR n 70% ER

- MOA: Increase dopamine and NE. Stimulants
- SEs: delayed onset of sleep, HA, decreased appetite = wt loss, slow growth, may exacerbate bipolar or psychotic condition. Heart problems pt, see cardiologist before.
Tics (most common with patch)

DDIs:
- MOA inhibitors
- Foods high in tyramine content
- TCAs
- Antihypertensive agents
- Sympathomimetics
- Warfarin
- Diamox: inc amphetamine [ ]

DOC
- School age children: amphetamine/methylphenidate
- Atomoxetine: use if fx object to tx with controlled sub
- Alpha-2 adrenergic: helpful when used combined

Indication: ADHD

2

Quillivant

- Age
- Dose
- Indication

Methylphenidate XR oral sol'n

- Age: > 6 y.o
- Dose: 20mg PO QAM. Shake bottle for 10s. Require pharmacist to reconstitution.
- Indication: ADHD

3

Daytrana

- Form
- Frequency
- Common SEs
- Indication

Methylphenidate Patch

- Transdermal patch. Worn daily 9hrs. Patch replaced QAM
- Tics (most common with patch)
- Indication: ADHD

4

Focalin

- Frequency: IR/ER
- Indication

Dexmethylphenidate

- IR: BID
- ER: QD in AM. May sprinked over applesauce
- Indication: ADHD

5

Dexedrine

- Indication

Dextroamphetamine

-Indication: Narcolepsy

6

Vyvanse

- CS
- MOA
- Indication
- Dose

Lisdexamfetamine SR/IR

- CS: II = Abuse. IV or intranasal is less abuse
- MOA: stimulant
- Indication: ADHD
- Dose: 30mg PO QAM. Max 70mg/d

7

Adderall IR/XR

- Indication
- Frequency: IR/XR

Dextroamphentamine + Amphetamine

- Indication ADHD, Narcolepsy
- IR: QD-BID given 1st thing in AM
- XR: QD

8

Provigil

- Indication
- Warnings

MODafinil

- Indication: narcolepsy and shift work sleep disorder

Warnings
- Psychiatric problems: anxiety, hallucinations, suicidal ideations
- Serious allergic rxn (SJS): similar to lamictal

9

Nuvigil

- Indication

ARModafinil

- Indication: Narcolepsy

10

Strattera

- MOA
- Indication
- Adv
- Dose
- Warning

Atomoxetine = not CS

- MOA: selective NE reuptake inhibitor
- Indication: ADHD
- Adv: good for pets with anxiety, insomnia, or substance abuse disorders
- Dose: max 100mg
- Warning: severe liver injury and failure, priapism

11

Intuniv
Tenex

- MOA
- Indication
- Dose
- SEs

Guanfacine = not CS

- MOA: non-stimulant. Stimulate alpha-2a adrenoreceptors
- Indication: ADHD (Tenex: tx high BP)
- Dose: QD tx for children age 6-17 y.o
- SEs: somnolence, HA, fatigue, abdominal pain.

12

Kapvay

- MOA
- Indication
- Dose

Clonidine ER Tab

- MOA: Alpha 2 agonist
- Indication: the 1st and only therapy approved for use with stimulant med for the tx of ADHD.
Can use a mono therapy
- Dose: start 0.1mg QD => titrate to BID

13

Adipex-P

- CS
- Indication

Phentermine

- CS IV
- Indication: weight loss

14

TENuate

- CS
- Indication

DIEThylpropion

- CS IV
- Indication: weight loss

15

Didrex

- CS
- Indication

Benzphetamine

- CS III
- Indication: weight loss

16

BONtril

- CS
- Indication

PhendiMETrazine

- CS III
- Indication: weight loss

17

Xenical

- MOA:
- CS
- Indication
- Dose
- Counseling points
- SEs

Orlistat

- MOA: gastric and pancreatic lipases inhibitors: inhibiting dietary fat absorption by 30%. Decrease TG and TC abs
- CS: none
- Indication: weight loss
- Dose: 60-120 mg TID w/ or up to 1H after meals.
Xenical (Rx): 120mg capsule
=> if a meal is missed or has no fat, skip the dose

SEs
- GI: flatus with discharge. Oily stool w/ spotting. Fecal urgency and inconinence
- Malabsorption of fat soluble carotenoid
- Malabsorption of fat sol it: ADEK

18

Belviq

- MOA
- CS Cat:
- Indication
- Dose
- Caution

Lorcaserin

- MOA: Selective 5-HT2C receptor agonist
- CS IV
- Indication: weight loss
- Dose: 10mg BID
- Caution: monitor for suicidal thought. Advise men to seek medical help for erection > 4H

19

Qsymia

- Indication
- CS Cat

Phentermine + topiramate ER capsule

- Indication: weight loss
- CS IV => Phentamine

20

Suprenza

- Form
- CS Cat
- Indication

Phentermine

- Form: ODT
- CS Cat: CS IV
- Indication: weight loss

21

Regimex

- Indication
- CS Category

Benzphetamine

- I: Weight loss
- CS III

22

Alli

- Dose

Orlistat

- (OTC): 60mg cap

23

Contrave

- Indication

Naltrexone and Bupropion

- Indication: Weight loss

24

Saxenda

Liraglutide

25

Dextrostat

- Indication

Dextroamphetamine

-Indication: Narcolepsy