Co-existing diseases- Neuromuscular diseases Flashcards Preview

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Flashcards in Co-existing diseases- Neuromuscular diseases Deck (38)
1

Muscular Dystrophy:
is it hereditary

yes

2

Muscular Dystrophy:
what is the hallmark description

painless degeneration and atrophy of skeletal muscle (associated w/ mental retardation)

3

Muscular Dystrophy:
what are the characteristics of Pseudohypertrophic muscular dystrophy?

CHF
Recurrent PNE
kyphoscoliosis
Hyperkalemia w/ SCh
Malignant hyperthermia suceptibility

4

Muscular Dystrophy:
Limb-Girdle muscular dystrophy characteristics

relatively benign

5

Muscular Dystrophy:
facioscapulahumeral, is the heart involved?

nope

6

Muscular Dystrophy:
2 characteristics associated with Nemaline Rod Muscuar Dystrophy

Micrognathia
Bulbar palsy

7

Muscular Dystrophy:
what is the most common and most severe of all the MDs

Duchenne's

8

Muscular Dystrophy: Duchenne's
it is ___-linked ______

X-linked recessive

9

Muscular Dystrophy: Duchenne's
when is the onset

early childhood

10

Muscular Dystrophy: Duchenne's
are kyphoscoliosis and hip and knee contractors common

yes

11

Muscular Dystrophy: Duchenne's
what EKG changes occur

prolonged PR and QRS
ST segment abnormalities
BBB
Q waves
Tall R waves

12

Muscular Dystrophy: Duchenne's
what happens to total lung capacity and residual volume

reduced

13

Muscular Dystrophy: Duchenne's
they are prone to recurrent what?

Pulmonary infection

14

Muscular Dystrophy: Duchenne's
why do u avoid SCh

increased risk of MH

15

Muscular Dystrophy: Duchenne's
is Neuromuscular monitoring mandatory?

yes

16

Multiple Sclerosis:
it is characterized by what?

random and multiple sites on demyelination of the corticospinal tract neurons in the brain and spinal cord, exclusive of peripheral neurons

17

Multiple Sclerosis:
S/S

Visual disturbances
Ataxia
Limb Paresthesia and weakness
Spastic paresis of skeletal muscle
exacerbations and remissions

18

Multiple Sclerosis:
what do you really want to avoid in these pt's

marked temp changes

19

Multiple Sclerosis:
also avoid what (bc it can exacerbate the symptoms)

stress

20

Multiple Sclerosis:
what can occur w/ SCh

hyperkalemia

21

Multiple Sclerosis:
can u do a spinal

questionable (but usually no)

22

Myasthenia Gravis:
is a chronic autoimmune disease inolving what?

the NMJ

23

Myasthenia Gravis:
it is characterized by weakness and rapid exhuastion of skeletal muscle with repetitive use; is there recovery with rest?

yes some recovery

24

Myasthenia Gravis:
S/S eyes

ptosis
Diplopia
(most common initial sign)

25

Myasthenia Gravis
why is there an increased risk of aspiration

weakness of pharyngeal and laryngeal muscles

26

Myasthenia Gravis:
is atrophy present?

no- there is asymmetric extremity skeletal muscle weakness

27

Myasthenia Gravis:
Complication r/t heart

Cardiomyopathy

28

Myasthenia Gravis:
any thyroid problems

hypothyroidism

29

Myasthenia Gravis:
treatments

Thymectomy
Plasmapheresis
Anti cholinesterase drugs
Corticosteroids

30

Myasthenia Gravis: Anesthesia
what would u want to avoid preop

opiods

31

Myasthenia Gravis: Anesthesia
what would you want to tell the pt (warn them about) in the prep period

poss mechanical ventilation postop

32

Myasthenia Gravis: Anesthesia
what should you do on induction?

short active IV drugs
Tracheal intubation without muscle relaxant

33

Parkinson's Disease:
is degenerative disease of the CNS characterized by loss of ________ fibers in the basal ganglia of the brain

dopaminergic

34

Parkinson's Disease:
_______ is an inhibitory neurotransmitter acting on the extrapyramidal motor system

dopamine

35

Parkinson's Disease:
S/S

Skeletal muscle rigidity
Resting tremor
Diaphragmatic spasms
Mental depression

36

Parkinson's Disease:
treatment are drugs times to do what?

increase the concentration of dopamine

37

Parkinson's Disease:
a common drug these pts are on

levodopa

38

Parkinson's Disease:
what do you want to avoid during anesthesia

drugs that w/ antidopaminergic effects
Droperidol
reglan

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