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Pneumologia > Colagenoses > Flashcards

Colagenoses Flashcards

1
Q

Deficiência de qual enzima predispõe toxicidade por Azatioprina ?

A

Tiopurina Metiltransferase (TPMT)

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2
Q

Padrão de FAN fortemente associado a AUSENCIA de autoimunidade ?

A

Nuclear Pontilhado fino DENSO

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3
Q

Quais patologias se associam ao Padrão Citoplasmático pontilhado fino ? E pontilhado grosso?

A

Fino:Miopatias inflamatórias e Síndrome antissintetase ( Anti- t- RNA- Sintetase)
Grosso: Anti mitocondria

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4
Q

Quais patologias se associam ao Padrão Nucleolar ?

A

Esclerose sistêmica (RNA polimerase/fibrinalinas)
Alta especificidade

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5
Q

Quais patologias se associam ao Padrão centromérico ?

A

Esclerose sistemica ou DMTC (Anti CENP)
Alta especificidade

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6
Q

Quais patologias se associam ao Padrão nuclear homogêneo ?

A

LES (Anti DNA e Anti histona)

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7
Q

Quais patologias se associam ao Padrão nuclear pontilhado grosso ?

A

LES e DMCT ( Anti RNP e SM)

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8
Q

Quais patologias se associam ao Padrão nuclear pontilhado fino ?

A

Sd Sjogren, LES (Padrão do Anti RO e Anti La)

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9
Q

Anticorpo associação de miosite + esclero

A

Anti Pm-scl (SCL 75-100)

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Pneumologia (11 decks)

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