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Flashcards in Common Lab Tests Deck (19):
1

CBC

includes:
1. RBC count
2. Hgb
3. Hematocrit (Hct)
4. RBC indices
5. WBC count and differential
6. platelet count

2

WBC count

useful for evaluating infection, neoplasm, allergy, and immunosuppression

3

Hct

measure of RBC precent of total blood volume

4

RBC indices

measures size and hgb content of RBC

includes
1. MCV
2. MCH
3. MCHC
4. RDW

5

MCV (mean corpuscular volume)

measure of average volume/size of single RBC

6

MCH (mean corpuscular hemoglobin)

measure of average mass of hgb within a single RBC

7

MCHC (mean corpuscular hemoglobin concentration)

measure of average hgb concentration within a single RBC

8

RDW

red blood cell distribution width
-measures variable in RBC size
-indicator of degree of anisocytosis

9

Basic metabolic panel

measure electrolytes, chemicals, metabolic end products & substrates

1. glucose
2. BUN
3. Creatinine
4. Na
5. K
6. Cl
7. Bicarb
8. Ca

10

BUN

-end product of metabolism (produced in liver)
-indirect measure of renal fxn & glomerular fxn
-measure of liver metabolic fxn

11

Creatinine

-Catabolic product of creatine phosphate (skeletal mm contraction)
-excreted by kidneys (direct measure of renal fxn)
-minimally affected by liver fxn
-elevation occurs slower than BUN

12

Ca2+

-used to evaluate parathyroid fxn & Ca metabolism
-used to monitor renal failure, renal transplantation, hyperparathyroidism, various malignancies, & Ca level when giving transfusions

13

Comprehensive metabolic panel (CMP)

includes BMP +
1. albumin
2. total protein
3. ALP
4. ALT
5. AST
6. bilirubin

14

Albumin

-Formed within liver & comprises 60% of total protein in blood
-maintains colloidal osmotic pressure & transports blood constituents
-measure of hepatic fxn and nutritional state

15

Total protein

prealbumin + albumin + globulins

16

ALP (alk phos)

detect and monitor hepatobiliary disease or bone disease with increased osteoblastic activity

17

ALT

-found primarily in liver
-injury/disease to parenchyma --> released into blood
-ID & monitor hepatocellular diseases of liver
-if jaundiced, implicates liver rather than RBC hemolysis

18

AST

-found in highly metabolic tissue (cardiac and skeletal mm & liver cells)
-disease/injury --> lysing of cells and release into blood
-elevation proportional to # of cells injured
-used for evaluation of suspected coronary artery disease or hepatocellular disease

19

Bilirubin

-end product of RBC metabolism
-component of bile
-direct (conjugated) and indirect (unconjugated)
-used to evaluate liver fxn
---hemolytic anemia work up in adults; jaundice in newborns
-jaundice occurs when total bilirubin > 2.5 mg/dL