Connective Tissue Flashcards Preview

Histology > Connective Tissue > Flashcards

Flashcards in Connective Tissue Deck (26):
1

Examples of indigenous cells of CT

fibroblasts, apipocytes, mesenchymal cells, osteogenic cells, chondrogenic cells

2

Examples of immigrant cells in CT

macrophages, mast cells, lymphocytes, plasma cells

3

fibroblasts

most common cell in CT, synthesize ECM components, can only visualize nuclei in stain

4

adipocytes

fat cells of CT

5

white adipocytes

unilocular and unstained, used from insulation, protection, and energy

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brown adipocytes

multilocular and unstained, rich in blood vessels, used for heat generation

7

plasma cells

differentiated B-lymphocytes (antibody factories), found in loose CT

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characteristics of plasma cells

clock face heterochromatin pattern, eccentric nucleus, prominent golgi and abundant ER

9

Mast cells

from blood, roles in innate immunity and allergic reations (anaphylaxis), found in loose CT

10

characteristics of mast cells

abundant granules (heparin and histamine), central nucleus, exhibit metachromasia

11

Macrophages

from blood monocytes, important in innate and acquired immunity, highly phagocytic

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characteristics of macrophages

very large, eosinophilic cytoplasm, phagocytic vacuoles

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Lympocytes

T and B cells, can recirculate in blood

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Characteristics of lymphocytes

small dark nuclei, very little cytoplasm

15

scurvy

Vitamin C deficiency, leads to improper crosslinking of collagen

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reticular fibers (locations)

lymphoid organs, liver, skin

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reticular fibers (characteristics)

type III collagen, highly branched, visualized by silver stain

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ground substance

composed of proteoglycans, GAGs and glycoproteins

19

Elastic fibers

requires fibrillin as a scaffold, sequesters TGF-beta

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Marfan syndrome

defect in fibrillin, important in elastic fibers (may be because of sequestration of TGF-beta)

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Loose conncetive tissue

CT with mostly ground substance

22

features of white adipose tissue

White and empty, large lipid vacuole, nucleus is pushed to the side

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Cutis Laxa

mutations in elastin genes, characterized by loose, hanging skin

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lamellar elastin

found in smooth muscle, synthesized by facular smooth muscle

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fibrillar elastic tissue

found in non vascular tissue, branched, forms complex with fibrillin

26

features of brown adipose tissue

smaller than white, large number of lipid droplets