Connective Tissue & Epithelium Flashcards Preview

HFF - Exam I > Connective Tissue & Epithelium > Flashcards

Flashcards in Connective Tissue & Epithelium Deck (25):
1

Name 3 primary functions of Epithelial Tissue

1. coverin, lining and protecting surfaces
2. absorption
2. Secretion

2

What are the 3 zones of the Basement membrane

1. lamina lucida
2. lamina densa
3. lamina fibroreticularis

Basement membrane acts as glue for epithelial cells to connect to connective tissue

3

Simple Squamos

Air sacs of lung, lining blood vessels. Allows diffusion

4

Simple Cuboidal

Secretory glands. Secretes and absorbs

5

Simple Columnar

Ciliated tissues in the bronchi, uterine tubes and uterus.

Absorbs: also secretes mucous and enzymes

6

Pseudostratified columnar

Ciliated tissues line the trachea and much of the RESPIRATORY Tract

7

Stratified squamos

Skin, esophogus, mouth and vagina. Protects against abrasions

8

Transitional epithelium

Lines the bladder! Lets tissue stretch

9

What are microfilaments composed of?

Actin

10

Explain Tight Junctions

Homotypical interactions between transmembrane proteins.
-Very narrow gaps, controls movement of stuff between cells.
-Bind to actin microfilaments

11

Name the 2 types of Connective tissue Proper

Loose and Dense (Regular/Irregular)

12

Name 4 Connective tissue type cells

1. fibroblast
2. adipocyte
3. macrophage
4. mast cells

13

What is Collagen

Most abundant protein in the body.
Extremely strong (example Dentin: Mostly is type I Collagen)

14

Proteoglycans

Main component of "ground substance"
- Mostly carbohydrate with a little bit of protein)
-Can serve to sequester growth factors in ECM and can help activate GF receptors

15

Glycoproteins

Mostly protein with a little of carbohydrate

16

Name the two types of Dense connective tissue and where they can be found in the body

Regular: Tendons and ligaments
Irregular: Deeper dermis, submucosa of intestine

17

What is a FIbroblast

Fibroblasts are the most common cells in connective tissue. Their main function is to maintain the structural integrity of the connective tissue by continuously secreting extracellular matrix proteins like collagens, glycosaminoglycans, and glycoproteins.

18

What makes Collagen so strong?

Collagen is rich in Proline & Lysine (Hydrogen bonding allows triple helical assembly)

19

What is the ground substance in connective tissue

Basically all the non fibrillar stuff that makes up the ECM of connective tissue. Mainly composed of proteoglycans and glycoproteins

20

What are Microtubules made of and what structure are they a part of in the cell

Made of tubulin,
essential part of the sytoskelon.

21

Cell-cell Adhesive junctions

Holds cells together to together cells
Cadherins (outside) Catinins (inside)
-Part of contact inhibition

22

Focal Adehesion Junctions

Holds cells to ECM
Similar to Cell-cell adhesions
-Difference is Integrins replace Cadherens.

23

What are Gap Junctions

Cell-cell aqueous pores.
ions and small water soluable molocules may pass. BUT nucelic acids, sugars and proteins tool large

24

What is a desmosome?

Involved in cell-cell adhesions
-Attach to intermediate filaments.
-Help resist shearing forces

25

What is a hemiadesomosme

Involved with ECM adhesion
-Attach to intermediate filaments
-Integrin transmembrane protein/ Remember (integrin replaces in cadheren in ECM adhesion)