Flashcards in Connective Tissue & Epithelium Deck (25):
Name 3 primary functions of Epithelial Tissue
1. coverin, lining and protecting surfaces
What are the 3 zones of the Basement membrane
1. lamina lucida
2. lamina densa
3. lamina fibroreticularis
Basement membrane acts as glue for epithelial cells to connect to connective tissue
Air sacs of lung, lining blood vessels. Allows diffusion
Secretory glands. Secretes and absorbs
Ciliated tissues in the bronchi, uterine tubes and uterus.
Absorbs: also secretes mucous and enzymes
Ciliated tissues line the trachea and much of the RESPIRATORY Tract
Skin, esophogus, mouth and vagina. Protects against abrasions
Lines the bladder! Lets tissue stretch
What are microfilaments composed of?
Explain Tight Junctions
Homotypical interactions between transmembrane proteins.
-Very narrow gaps, controls movement of stuff between cells.
-Bind to actin microfilaments
Name the 2 types of Connective tissue Proper
Loose and Dense (Regular/Irregular)
Name 4 Connective tissue type cells
4. mast cells
What is Collagen
Most abundant protein in the body.
Extremely strong (example Dentin: Mostly is type I Collagen)
Main component of "ground substance"
- Mostly carbohydrate with a little bit of protein)
-Can serve to sequester growth factors in ECM and can help activate GF receptors
Mostly protein with a little of carbohydrate
Name the two types of Dense connective tissue and where they can be found in the body
Regular: Tendons and ligaments
Irregular: Deeper dermis, submucosa of intestine
What is a FIbroblast
Fibroblasts are the most common cells in connective tissue. Their main function is to maintain the structural integrity of the connective tissue by continuously secreting extracellular matrix proteins like collagens, glycosaminoglycans, and glycoproteins.
What makes Collagen so strong?
Collagen is rich in Proline & Lysine (Hydrogen bonding allows triple helical assembly)
What is the ground substance in connective tissue
Basically all the non fibrillar stuff that makes up the ECM of connective tissue. Mainly composed of proteoglycans and glycoproteins
What are Microtubules made of and what structure are they a part of in the cell
Made of tubulin,
essential part of the sytoskelon.
Cell-cell Adhesive junctions
Holds cells together to together cells
Cadherins (outside) Catinins (inside)
-Part of contact inhibition
Focal Adehesion Junctions
Holds cells to ECM
Similar to Cell-cell adhesions
-Difference is Integrins replace Cadherens.
What are Gap Junctions
Cell-cell aqueous pores.
ions and small water soluable molocules may pass. BUT nucelic acids, sugars and proteins tool large
What is a desmosome?
Involved in cell-cell adhesions
-Attach to intermediate filaments.
-Help resist shearing forces