Coronary & Pulmonary Circulation Flashcards Preview

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Flashcards in Coronary & Pulmonary Circulation Deck (19):
1

where do most transmural MIs occur?

anterior LV or inferior LV

2

which leads to use to look for MI in anterior LV?

precordial Leads, I, aVL

3

which leads to use to look for MI in inferior LV?

leads II, III, aVF

4

The heart is perfused primarily during what phase of the cardiac cycle?

ventricular diastole

5

being able to maintain a flatline of blood flow over a range of pressure

autoregulation

6

flow = ?

flow = change in pressure / Resistance

7

myogenic mechanism: For constant flow to be maintained, _________in ΔP must be met by _________ in R

myogenic mechanism: For constant flow to be maintained, an increase in ΔP must be met by an increase in R

8

how is the myogenic mechanism accomplished?

through stretch-activated channels to increase vascular contraction.

9

what is the coronary reserve related to?

how well the arteries can vasodilate

10

you would expect a ______in coronary reserve in heart failure

reduction (lessened ability to produce NO to induce vasodilation)

11

increased metabolism-->incr hypoxia-->incr ATP turnover results in what?

incr cellular adenosine accumulation-->activates vasodilation

12

what are the 2 phases of sympathetic regulation of coronary circulation?

phase 1: vasoconstriction via NE
phase 2: metabolic vasodilation, incr force of contraction

13

pulmonary vs coronary anatomy: pulmonary have _____vessels, _____internal diameter lumens, ______ vascular smotth muscle, _____resistance

pulmonary have thinner vessels, greater internal diameter lumens, less vascular smotth muscle, lower resistance

14

does zone 1 or 3 have a higher perfusion pressure?

zone 3 (gravity!)

15

what mediates vasodilation in response to hypoxia in coronary vasculature?

adenosine

16

in pulmonary circulation, hypoxia mediates what effect?

vasoconstriction

17

opening of previously clsoed capillaries

recruitment (mechanism of passive regualtion)

18

accomodation of incr blood volume

distension (mechanism of passive regualtion)

19

chronic hypoxemia can result in _____ ventricular failure

right