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Flashcards in Crossover Deck (136)
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1

False about Natural penicillin:

A. Good against Streptococci and Meningococci
B. Good against Staphylococci
C. Repository formula= Penicillin G Benzathine
D. Oral preparation= Phenoxymethy penicillin

B

2

In addition to Penicillin G, aminopenicillin has added activity to:

A. Corynebacterium diphtheriae
B. Staphylococcus
C. Listeria monocytogenes
D. Streptococcus

C

3

Tue of Oxacillin except:

A. Has an activity to Staphylococcus
B. Has an activity to Klebsiella pneumoniae
C. Primarily used for parenteral treatment of serious S. pneumoniae
D. Has an activity to Streptococcus

B

4

True for Piperacillin-Tozabactam except:

A. Most broad spectrum available in the Philippines
B. With anaerobic activity
C. For MRSA
D. For P. aeruginosa

C

5

Rina is a 2 day old with untreated syphilis. Which penicillin would be given?

a. piperacilin-tazobactam
b. Co-amoxiclav
c. Meropenem
d. Penicillin G

D

6

compared to a 1st gen cephalosporin, a 3rd gen cephalosporin would be expected to exhibit?

A. improved activity against certain gram negative bacteria
B. lower levels of activity in the CSF
C. improved inhibition of folate synthesis by sensitive bacteria
D. AOTA

A

7

Which among the ff statements about cefazolin is FALSE:

A. It is effective against Staphylococcus aureus and Streptococcus
B. It has good oral bioavailability.
C. It may used for skin infections and cellulitis.
D. It has no activity against enterococcus.

B

8

What is the advantage of using Cefepime over Ceftazidime?

a. lesser activity against gram positive bacteria
b. higher activity against Chlamydia
c. better activity against gram negative bacteria
d. should be used in all cases in the ER

C

9

Cefuroxime is useful for treatment of infections caused by the following pathogens except:

a. Haemophilus influenza
b. E. coli
c. Streptococcus pneumonia
d. Legionella

C

10

[T/F] All clinically useful antibacterials are selectively toxic to microorganisms

F

11

[T/F] For an antibacterial antibiotic to be effective, it must first gain access to the target sites of action, that is or in the human host cell.

T

12

[T/F] The basic mechanism of action of beta-lactam antibiotics is inhibition of nucleic acid synthesis or function

F

13

[T/F] Compared with other pharmacological agents, antibacterial chemotherapeutic agents are reasonably safe.

F

14

[T/F] The word antibiotic is now often used to include antimicrobial agents, produced by microorganisms and those that are totally synthetic

F

15

Amoxicillin

A. Aminopenicillin
B. Carboxy Penicillin
C. Natural Penicillin
D. Penicillinase-resistant penicillin
E. Ureide Penicillin

A

16

Benzyl Penicillin

A. Aminopenicillin
B. Carboxy Penicillin
C. Natural Penicillin
D. Penicillinase-resistant penicillin
E. Ureide Penicillin

C

17

Carbenicillin

A. Aminopenicillin
B. Carboxy Penicillin
C. Natural Penicillin
D. Penicillinase-resistant penicillin
E. Ureide Penicillin

B

18

Cloxacillin

A. Aminopenicillin
B. Carboxy Penicillin
C. Natural Penicillin
D. Penicillinase-resistant penicillin
E. Ureide Penicillin

D

19

Piperacillin

A. Aminopenicillin
B. Carboxy Penicillin
C. Natural Penicillin
D. Penicillinase-resistant penicillin
E. Ureide Penicillin

E

20

The beta-lactam antibacterial antibiotics include the following EXCEPT:

A. Penicillin V
B. Cefuroxime
C. Meropenem
D. Cilastatin

D

21

This third generation cephalosporin is relatively resistant to hydrolysis by beta-lactamases and has the broadest gram-negative spectrum

A. Cefepime
B. Ceftriaxone
C. Cefuroxime
D. Cephalexin

B

22

Penicillin of choice for Streptococcus pyogenes is

A. Penicillin G
B. Penicillin V
C. Cloxacillin
D. Amoxicillin

A

23

Depot formulations of Penicillin G i.e., Benzathine Penicillin G and Procaine Penicillin G are inappropriate for meningitis

A. True
B. False

A

24

The activity of extended spectrum penicillins goes beyond that of the aminopenicillins as it is active against

A. Staphylococci
B. Streptococci
C. Enterococci
D. Pseudomonas

D

25

[T/F] Appropriate specimen collection from the infected organ system should be done day after starting antibiotic therapy

F

26

[T/F] Having a previous hypersensitivity reaction to penicillin G, would also predispose the patient to having a hypersensitivity reaction to another penicillin like piperacillin

F

27

[T/F] in treating bacterial infection in immunocompromised patient, such as those with leukemia a bacteriostactic agent is sufficient

F

28

The Beta-Lactam Antibacterial antibiotics are selectively toxic. Selective toxicity is

a. What the drug does to the patient
b. What the patient does to the drug
c. What the pathogen does to the patient
d. What the drug does to the pathogen
e. What the pathogen does to the drug

D

29

All of these drugs are beta-lactam antibiotics EXCEPT

a. Ampicillin
b. Aztreonam
c. Cephalexin
d. Gentamycin
e. Imipenem

D

30

The basic mechanism of action of beta-lactam antibiotics is

a. Inhibition of bacterial protein synthesis
b. Inhibition of mycolic acid synthesis
c. Inhibition of cell wall synthesis
d. Inhibition of cell membrane function
e. Interference of microbial folic acid synthesis

C