CV Histology Flashcards Preview

Cardiology > CV Histology > Flashcards

Flashcards in CV Histology Deck (11):
1

What are the three layers of an artery?

Intima, media, adventitia 

A image thumb
2

What does the intima include?

Endothelium, basal lamina, myointimal cells (sm muscle, produce collgen, can phagocytose)

3

What are the functions of endothelium?

Barrier: tight junctions
Filter/transport
Secretion: vasodilation/vasoconstriction
Cell growth
Clotting: inhibit/promote
Lipoprotein metabolism (LDL, VLDL)
Produce ECM
Immunologic

4

What does the media include?

Elastic fibers, smooth muscles cells (make collagen, elastin, proteoglycans), innervation (adrenergic=constriction, cholinergic= dilation, afferent for pressure/CO2)

5

What does the adventitia include?

Connective tissue, vasa vasorum= vessels that supply the media

6

What are the layers of the heart?

Epicardium = mesothelium, epicardial fat, then myocardium

Myocardium = myocytes

Endocardium= inside of heart

7

What is the constitution of the myocardium?

Myocytes = contract
Myocytes secrete BNP when stretched (atrial cells)-- helps kidney secrete water, biomarker of heart failure
Myocytes also involved in conduction
Nerves
Connective tissue
Vessels
Leukocytes

8

What type of cells is the conduction system of the heart made from?

Specialized myocytes that don't contract, they conduct

9

What is the endocardium made from?

Collagen, elastic fibers, smooth muscle cells, endothelium

10

What determines the thickness of endocardium?

Thickness determined by pressure and turbulence

11

What are the layers of valves?

Spongiosa = looser, connective tissue

Fibrosa = denser connective tissue

Covered by endothelium

Normally don't have vessels - sign of pathology