CV-HTN

Question 1

What are BP goals with HTN

Answer 1

<130/80, DM/CKI 130/80

Question 2

Which is the most effective drug for HTN?

Answer 2

cholorthalidone

Question 3

What is order agents for heart failure

Answer 3

1. ACE 2. Cholorthalidone-sx, HCTZ, 2. BB 3. ARB, AA

Question 4

What is order agents for POST MI

Answer 4

1. BB, 2. ACEI

Question 5

What is order agents for CAD unstable, stable

Answer 5

1. BB or CCB 2. ACEI 3. Cholorthalidone, HCTZ

Question 6

What is order agents for DM w/ HTN

Answer 6

1. ACEI/ARB, 2.Cholorthalidone, HCTZ, 3. BB/CCB

Question 7

What is order agents for CKD ?

Answer 7

1. ACEI/ ARB

Question 8

What is order agents for recurrent stroke?

Answer 8

1. Cholorthalidone, HCTZ, 2. ACEI

Question 9

What is main effect of ACEI?

Answer 9

DEC BP peripheral. DEC AGII=DEC preload

Question 10

How does ACEI affect GFR?

Answer 10

Little effect on CO, HR or GFR

Question 11

What should not be combined with ACEI?

Answer 11

ARB

Question 12

Which drug DEC contractiliy, and blunts SNS in heart?

Answer 12

BB- NOT 1st line unless comorbitiies

Question 13

What should be consider in BB?

Answer 13

Lowers SBP 10-20, DBP 10-5

Question 14

Are BB ok in AA and pregnant women?

Answer 14

Not AA. Atenolol NOT OK

Question 15

Which block smooth muscle and vasodiates?

Answer 15

Ca channel blockers. Block AV node= DEC HR and contractily

Question 16

When are CC and Diurectics 1st line?

Answer 16

AA and elderly

Question 17

Which DEC CO, GFR, RBF?

Answer 17

Diurectic-thaiz

Question 18

Which is most favorable in renal fucntin for mortaliy?

Answer 18

Cholorthalidone, HCTZ

Question 19

Diruetcts have ADE of what?

Answer 19

HYPOkalemi, blunted Twaves

Question 20

Mr. Thal develops hypokalemia, what is DOC?

Answer 20

Cholorthalidone, HCTZ

Question 21

What is common dose for diuretcis?

Answer 21

12.5-25mg PO

Question 22

Mr. Thal is taking digoxin, what is important?

Answer 22

Monitor TI

Question 23

What HTN meds are avoided in pregancy?

Answer 23

ACE, ARB, DRI (direct renin inhib

Question 24

NSAIDs are caution during Anti HTN bc

Answer 24

NSAIDs blcok Cox 1 and 2. Raise BP d/t NA/H2O retention. Blunt anti-HTN

Question 25

What is DOC for volume overload?

Answer 25

Loop Diuretics

Question 26

What is the only DRI for anti-HTN?

Answer 26

Aliskren- renin inhibotr. INC CK/CPK level-inflammatory induce, when tissue damage is rampant

Question 27

Atrovastatin, ketoconazol due what to DRI?

Answer 27

INC Aliskiren levels

Question 28

What should not be combined with DRI?

Answer 28

ACE, ARB, in DM or AKI, CKI

Question 29

What are the alpha-blockers?

Answer 29

Prazosin, Terazosin, Doxazosin

Question 30

Mr. Mean has PHM of BPH a war veteren w/ h/o PTSD. He is here for his BP of 150/89/ What agent will treat all of d/o?

Answer 30

Zozin- alpha-blocker

Question 31

What does the alpha recpetor do in the body?

Answer 31

Potent vasocontrcitor. Alpha-blk= vasodiation. LIVER cleared-LFTs?

Question 32

What are DI with Alpha Blockers?

Answer 32

BB inc orhtostasis, CCB- verapamil- will not get cleared

Question 33

During pt education with Alpha blockers what is concern?

Answer 33

May cause syncope sit to stand. MSK should constrict when standing help BF to return to brain and heart, thus RX vasodialtes, so no return

Question 34

Ms. Stacy is 32y preg w/ HTN and risk of preclampsia. What RX is best

Answer 34

Alpha agonist- Methyldopa

Question 35

Which non-stimulant drug is used for HTN an d ADHD

Answer 35

Clonidine, Guafacine

Question 36

Mr. Thal HTN is 200/120, what med can be used?

Answer 36

Clonidine, Methydopa, Guanfacine, Guanabenz

Question 37

How should the alpah agonist be tapered?

Answer 37

Discontine slowly due to rebound HTN, HA, palpitations

Question 38

What effect do alpha agonist have?

Answer 38

Anit cholinergic- INHIB PNS. dry as a bone, red as beet, mad as hatter, hot, blind

Question 39

Which NT will alpha agonist block?

Answer 39

NOREpi

Question 40

What drug is last choic for CKI stage 4-5?

Answer 40

Direct Arterial Vasodialtors- Hydrlazine, Minoxidil

Question 41

What are some ADE of DAVs

Answer 41

1. HA 2. Reflex HTN 3. BB will enhance 4. Check LFTs

Question 42

What depletes catacholimens with a slow onset of HTN effects?

Answer 42

Peripheral Andrenergic Inhib. 2. Reserpine- 3rd line w/ Diurectics 3. Guanadrel/Guanethidine

Question 43

What stomach d/o should be avoid w/ Resperine?

Answer 43

Pelvic Ulcer Dz

Question 44

Which peripheral adreneric (SNS) inhib has BBW for orthostaic hypotension?

Answer 44

Guanadrel/Guanethidine

Question 45

What med used or ED/urgernt accumulate metabolinte thiocyanate in AKI?

Answer 45

Nitropruside. NO- potent vasodialtor, rapid control for BP

Question 46

What is adminsraction of HTN ED methods?

Answer 46

IV

Question 47

What RX is ideal for pheochromocytoma?

Answer 47

malginant HTN TX with PHENTOLAMINE

Question 48

FENOLDOPAM is a vasodialtor of which receptors?

Answer 48

D1, a2 agonist

Question 49

What is MC urgern meds for agina and HTN?

Answer 49

Nitroglycerin- dialates venous and coronary artery. BUT severe HA

Question 50

WHihc drugs are used for RHF?

Answer 50

RHF-SOB, presyncope, edema-legs, abdomen= Pulmonary Arterial Hypertension. 1.Epprostenol 2. Treprostinil 3. Lloprost 4. Bosentan 5. Ambrisentan

Question 51

What is prostacyclin analog, vasodialotr, platlet aggregator inhbi?

Answer 51

The prost and sentans!

Question 52

What are common ADE for prosts and sentans?

Answer 52

Jaw pain, GAD, N/V, hypotension

Question 53

Which prost induce infx d/t IV catheter in for long time?

Answer 53

Epoprostenol

Question 54

Which sentan is LFT monitored?

Answer 54

Bosentan