Cytokinse Flashcards
(25 cards)
Which cell produce IL1
Macrophage
Which cell produce IL2
T-cell
Which cell produce IL3
T-cell
Which cell produce IL4
Th2
Which cell produce IL5
Th2
Which cell produce IL6
Macrophage
Which cell produce IL8
Macrophage
Which cell produce IL10
Th2
Which cell produce IL12
Macrophage
IL1 also called
Osteoclast activating factor
⬆️ IL1 lead to
- Fever
- Osteoporosis
IL2 function
Autocrine : exit from t-cell and stimulate the T-cell to proliferation
IL3 function
- Stimulate the proliferation of myeloid cell origin
- Stimulate the proliferation of granulocytes
IL4 function
- Convert IgM to IgE
- ⬆️ IgG
- ⬆️ Th2
IL5 function
- Convert IgM to IgA
- Increase eosinophils proliferation in bone marrow
IL6 function
- Acute phase reactant
- Produce fever
Inducer of phagocytosis
- IgG
- C3b
- CRP
- IL8
Which cell produce IL10
Th2
IL10 function
Inhibit immune system
IL11 function
⬆️ platelets
Function of IL7
Convert the steam cell CD34 to lymphoid cell
Activation of NK by
- IFN- alpha
- IFN-Beta
NK cell activate the
IFN-gamma
In case of transplant organ which IL most inhibit
IL-2, because Th1 activate CD8 that attack the graft by IL2