Cytokinse Flashcards

(25 cards)

1
Q

Which cell produce IL1

A

Macrophage

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2
Q

Which cell produce IL2

A

T-cell

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3
Q

Which cell produce IL3

A

T-cell

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4
Q

Which cell produce IL4

A

Th2

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5
Q

Which cell produce IL5

A

Th2

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6
Q

Which cell produce IL6

A

Macrophage

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7
Q

Which cell produce IL8

A

Macrophage

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8
Q

Which cell produce IL10

A

Th2

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9
Q

Which cell produce IL12

A

Macrophage

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10
Q

IL1 also called

A

Osteoclast activating factor

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11
Q

⬆️ IL1 lead to

A
  1. Fever
  2. Osteoporosis
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12
Q

IL2 function

A

Autocrine : exit from t-cell and stimulate the T-cell to proliferation

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13
Q

IL3 function

A
  1. Stimulate the proliferation of myeloid cell origin
  2. Stimulate the proliferation of granulocytes
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14
Q

IL4 function

A
  1. Convert IgM to IgE
  2. ⬆️ IgG
  3. ⬆️ Th2
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15
Q

IL5 function

A
  1. Convert IgM to IgA
  2. Increase eosinophils proliferation in bone marrow
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16
Q

IL6 function

A
  1. Acute phase reactant
  2. Produce fever
17
Q

Inducer of phagocytosis

A
  1. IgG
  2. C3b
  3. CRP
  4. IL8
18
Q

Which cell produce IL10

19
Q

IL10 function

A

Inhibit immune system

20
Q

IL11 function

A

⬆️ platelets

21
Q

Function of IL7

A

Convert the steam cell CD34 to lymphoid cell

22
Q

Activation of NK by

A
  1. IFN- alpha
  2. IFN-Beta
23
Q

NK cell activate the

24
Q

In case of transplant organ which IL most inhibit

A

IL-2, because Th1 activate CD8 that attack the graft by IL2

25
In case of tumor, which IL most increase it
IL2 because the Th1 activate the CD8 that attack the tumor by IL2