Derm emergencies Flashcards
1
Q
what is overlap of steven johnson and toxic epidermal necrolysis
A
SJS - 10% body area
TEN - 30%
2
Q
morpho of SJS
A
- dusky tender skin
- mucous membrane involved
- bullae
- skin sloughing
- atypical targets
3
Q
cause of SJS
A
DRUGS
- Abx
- anticonvusants
- NSAIDs
- allopurinol
4
Q
mgmt of SJS
A
- diagnose early
- STOP DRUG
- supprtive care - burn unit
- immunosppuress
5
Q
what is henoch sheinlen pupura
A
- inflammation and nercrosis of blood vessels
6
Q
skin manifestations of HSP
A
- palpable purpura
- vesicles
- livedo - laceliek stuff
- ulcers and nodules
7
Q
causes of vascultis
A
- just about anything
8
Q
how is vasculitis classified
A
by size of vessel
9
Q
how to treat vasculitis
A
depends on where
systemic workup
skin - nothing
other - steroids, cyclophosphamide
10
Q
what is pemphigus vulgaris
A
- starts with oral sores
- moves on to progression of flaccid blisters all over
11
Q
cause of pemphigus vulgaris
A
autoimune
12
Q
Tx of pemphigus vulgaris
A
- high dose immunosupressants
- prednisone
- other steroid sparing agents
13
Q
what is bullous pemphigoid
A
- tense blisters of urticarial skin
- pruritis
- usually elderly
14
Q
cause of bullous pemphigoid
A
- drugs
- autoimune
15
Q
mgmt of bullous pemphigoid
A
- prednisone
- if mild can try topical clobetasol
16
Q
what is nec fascitis
A
- infection of sub-cut fat and fascia
- ## rapidly progressive necrosis
17
Q
signs and Sx of nec fasc
A
- exquisite tenderness
- erythema evolving to dusky grey
- woody erethyma
- maloderous discharge
18
Q
Tx of nec fasc
A
- stabilize and admit
- broad spectrum ABx
- surgical debridment
19
Q
what is drug hypersensitivity syndrome
A
- 2-6 weeks after the drug
- fever/malaise
- mobiliform rash
- facial edema
- lymphadenopathy
20
Q
Tx of drug hypersens
A
- stop the drug
- ## supportive care
