Derm Wrong

Question 1

Function of apocrine glands

Answer 1

secrete oily scented fluid found in axillae and perineum

Question 2

Function of eccrine glands

Answer 2

secrete sweat for temperature regulation, found everywhere

Question 3

Label it (left to right)

Answer 3

Question 4

How would this lesion be described

Answer 4

Lichenification (feature is leathery skin)

Question 5

What term can be used to describe the heel of this patient?

Answer 5

Maceration
(What happens to the skin after a prolonged exposure to moisture)

Question 6

What term would describe what has happened to the skin of this patient?

Answer 6

Erosion (the loss of epidermis)

Question 7

How would you describe this lesion? (1word)

Answer 7

Nodule (a rounded, irregular mass)

Question 8

How would you describe this lesion (1word)

Answer 8

Papule (small inflammatory spot, no pus)

Question 9

How would you describe this lesion?

Answer 9

Macule (skin discolouration)

Question 10

What would you describe these lesions as ? (1word)

Answer 10

Vesicles (small +fluid filled)

Question 11

Where are hemi-desmosomes found

Answer 11

Dermo-epidermal junction

(They stick basal layer to basement membrane)

Question 12

What enzyme deficency causes poryphtria cutanea tarda
what poryphorin is accumulated

Features of presentation?

Answer 12

Uroporphyinogen decarboxylase

uroporphyrinigen 3

middle aged men
blistering in sun> scarring
Excessive hair growth (hypertrichosis)

Question 13

What enzyme deficency causes erythopoietic protoporphyria
what poryphoria is built up

Features of the presentation

Answer 13

Ferrochtelqse defiency
protoporphyrin IX

Young child, discomfort after sun, no rash

Question 14

What enzyme deficiency causes acute intermittient porphoryia
what poryphoria is built up

Features of presentation

Answer 14

Porphobilinogen deaminase
porphbilinogen (aka hydroxy)

woman, Acute neurotoxic reaction in tissues, mood disturbance

Question 15

List the diff types of hypersensitivity and give a brief description of each

Answer 15

Type I- instant, IgE mediated, allergic
T II- IgG, IgM, blood serum sickness (cytotoxic)
T III- IgG, IgM, immune complex
TIV- T cell mediated, delayed, contact dermatitis

Question 16

ABPI ranges and what it means

Answer 16

0.8-1.3 normal
<0.8 = arterial disease
>1.3= arterial calcification eg. RA

Question 17

what depth of SCC is associated with good/bad prognosis

Answer 17

<2mm good prognosis
>4mm bad prognosis

Question 18

“slap cheek syndrome” is …
Caused by…
common in ages of…

Answer 18

erythema infectiosum
Parovirus
3-15years

Question 19

herald patch is a sign of what disease
common in ages….

Answer 19

pityriasis rosea
10y-35y
Herald patch which disapears then get loads of small red lesions on trunk/back following dermatomes

Question 20

what can exacerbate psoriasis and cause guttat psoriasis specifically

Answer 20

streptococcal throat infection

Question 21

common causes of exacerbation of plaque psoriasis

Answer 21

alcohol, propanolol

Question 22

what diseases is erythema nodosum associated with

Answer 22

IBD, tuberculosis and sarcoidosis

Question 23

What causes albinism

Answer 23

Inability to synthesise tyrosine

Question 24

What causes vitiligo

Answer 24

Autoimmune destruction of melanocytes

Question 25

during foetal development where do melanocytes migrate from

Answer 25

neural crest

Question 26

are mucosal membranes keratnised

Answer 26

no

Question 27

where are melanocytes found in the skin

Answer 27

deep layer of the dermis

Question 28

what layers of the skin do eccrine, apocrine and sebacous gladns and hair follicle originate

Answer 28

eccrine and apocrine- epidermis sebacous- mid dermis hair follicle- subcutis

Question 29

what cells carry out vitamin d metabolism in the skin

Answer 29

keratinocytes

Question 30

what do venous ulcers present as

Answer 30

shallow ulcers, granulated base medial malleoulus

Question 31

arterial ulcers presentation

Answer 31

punched out lesions, atrophied skin, shiny skin, cold skin and reduced pulse

Question 32

neuropathic ulcer presentation

Answer 32

punched out!, bottom of feet usually, (kind of hard sometimes to differentiaite between arterial and neuropathic however defining features are neuropathic will still have strong pulse and warm skin)

Question 33

kapsoi sarcoma presentation and causitive organism

Answer 33

HIV + raised purple coloured patches on trunk and lesions in mouth human herpes virus 8

Question 34

what type of melanoma is often seen in dark skinned individuals

Answer 34

acral lentignous

Question 35

what diseases present with a butterfly rash and what differentiates them

Answer 35

SLE: joint pain, fatigue, raynauds etc Eryispleas: ACUTE, unwell (type of cellulitis) rosacea: systemically well, spotty etc

Question 36

necrobiosis lipdoidica px

Answer 36

orange, brown atrophied skin that is shiny with telangiectasia and associated with diabetes

Question 37

Slapped cheek child what diagnosis

Answer 37

ERYTHEMA INFECTIOSUM

Question 38

Kawasaki disease presentation

Answer 38

fissured lips, friable tongue, bilateral conjunctival injection, rash on hands feet, elbows

Question 39

most agressive melanoma

Answer 39

nodular, ( 2nd most common)

Question 40

most common melanoma

Answer 40

superficial spreading

Question 41

dermatitis herpeticum causative organism

Answer 41

HSV NOT HPV