Developmental disorders Flashcards
Age of onset:
childhood
Neurodevelopmental
Age of onset:
adolescence/young adulthood
Internalizing
externalizing
disorder
Internalizing
- negative affectivity (emotional, somatic)
externalizing
maladaptive behaviour
social actions
neurocognitive (adulthood, geriatrics)
What are the individual differences in age of onset?
Subtypes
specifiers
Subtypes:
groups that share certain distinct characteristics (refer to prognosis of “course”
specifiers:
inform treatment plans
-refer to specific characteristics
Categorization and causes
what is the difference in acuired vs. Inherited
what is the problem
Gained after birth vs. genetic transmission
The problem is that they are not mutually exclusive definitions
Environment categorization and causes
Diathesis-stress
Differential susceptibility
categorization and causes
Diathesis-stress: Negative factors
Differential susceptibility:
positive and negative factors
Individual
categorization and causes
Diathesis-stress
Differential susceptibility
categorization and causes
Diathesis-stress
vulnerability
Differential susceptibility
susceptibility
Results
categorization and causes
Diathesis-stress
Differential susceptibility
categorization and causes
Diathesis-stress:
risk
Differential susceptibility:
plasticity
Condition
categorization and causes
Diathesis-stress
Differential susceptibility
categorization and causes
Diathesis-stress:
neurodevelopmental
Differential susceptibility
disorder
Categorization and causes
acquired vs. inherited
what is the problem
Reductionism
the supposition that an event/situation is caused by one factor
genotype does not equal phenotypes
Categorization and causes
acquired vs. inherited
What is Epigenetics
Changes in gene function as a result of environmental influences
structural damage toxicity
environmental deprivation
Geschwind-Galaburda theory
Neurodevelopmental disorders
Risks
cellular development affects what?
connectivity affects what?
earlier onset results in what?
Genetically speaking
Cellular development affects physiology, connectivity affects psychology
exceptions are rare but possible
earlier onset, the more sever the deficit
Neurodevelopmental disorders
Risks
XY chromosome
Lack of protective factors; Y more unstable, only supports sex development, alteration increase susceptibility
Neurodevelopmental disorders
Risks
Low birth weight
Proxy; associated with many (if not all) genetic/environmental factors
Neurodevelopmental disorders
Risks
Deprivation
O2 folic acid omega 3
Neurodevelopmental disorders
Risks
Genetic
Duplication: An additional chromosome
deletion: missing chromosome (some cases of only alleles)
Mosiacism: A blend of maternal/paternal genes across the body
-may explain variations in “phenotype” or syndromes