Developmental Genetics Flashcards
(8 cards)
The changing of a cell’s developmental fate
Transdetermination
The setting of a cell’s particular development
Developmental Fate
The process of creating final cell types out of stem cells
Cell Differentiation
ABC Whorls
Outer --> Inner A: Sepal AB: Petal BC: Stamen C: Carpel
Maternally Expressed Genes
1
Bicoid Transcript is deposited in the anterior end
Nanos Transcript is deposited in the posterior end
-Deposited by nurse cells in the mother
-Transcripts are then translated
Gap Genes
2
Divide ends into regions
-Hunchback: Inhibited by nanos and enhanced by bicoid
-Other gap genes follow due to concentrations of hunchback, biocoid, and nanos proteins
Pair-Rule Genes
3
Divide gap gene regions into segments
-Even-skipped gene expressed in odd segments
-Odd-skipped gene expressed in even segments
Homeotic Genes
4
Affect the identity of pair-rule gene segments
-Ultrabithorax (Ubx): Distinguishes between Thoracic 2 (T2) and T3; only expressed in T3; suppresses T1 and T2 genes, leading to T2 genes in T3 if supressed
-Antennapedia (Antp): Expressed only in T1 and T2; controls formation of legs and other thoracic structures
(Hox genes in mammals)