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Flashcards in Diabetes Deck (18):
1

What are three oral hypoglycemic drugs?

Glipizide, metformin, and rosiglitazone

2

Wht are the two insulin preparations approved for veterinary use?

Prozinc and Vetsulin

3

What preparation (concentration) do veterinary insulin preperations come in?

40 insulin units/mL (Human comes in 100IU/mL)

4

Canines are 4x more sensitive to which type of insulin?

Detemir

5

Examples of short acting insulins

LISPRO, Regular insulin, and Humulin-R

6

How is Short acting insulin administered?

IV (fast onset, short duration, use CRI)
IM (slightly slower onset, short duration, need to give TID)
*Not going to be used as a maintenence tx for stable diabetic patients

7

What are examples of intermediate acting insulins?

LENTE insulin, Humulin-N, Vetsulin, and Humulin 70/30

8

How are intermediate acting insulins administered?

SC only.

quick onset, intermediate duration

9

T/F amorphous crystals (such as zinc) allow the insulin to be absorbed quickly

False.
Allows the insulin to be absorbed gradually

10

What is Humulin 70/30?

70% NPH (Humulin-N) and 30% Regular to allow for a faster onset

11

What are the three long-acting insulins?

Prozinc, Glargine, and Detemir

12

How do you give long acting insulins?

give SC inly once a day

13

WHat species is prozinc used for?

Cats

14

How does Glargine work?

acidic pH and microprecipitates allow for very gradual absorption.

15

How do you treat a patient with diabetic ketoacidosis?

- Fluids 0.9% NaCl
- Regular insulin started as CRI
- Add dextrose to fluid if patient not eating

16

How to treat Hyperosmolar diabetic/Coma?

- Fluids
- Regular insulin CRI (after rehydration)
*bring glucose down slowly after rehydration

17

What is the somogyi phenomenom?

rebound hyperglycemia if blood glucose drops too low too quickly

18

What is acarbose used for?

Reduces post carbohydrate eating hyperglycemia but inhibiting alpha amylases and brush border oligosaccharides (essentially stops absorption of carbs)