Diabetic Patient Long-Term Care and Management Flashcards Preview

Endo/Repro Exam 2 > Diabetic Patient Long-Term Care and Management > Flashcards

Flashcards in Diabetic Patient Long-Term Care and Management Deck (20):
1

What is key in the treatment of diabetic patients?

Key is control of blood pressure, lipids, insulin resistance, clotting risks not merely blood glucose

2

How is Type II differentiated from Type I diabetes?

Type II doesn't have ketosis, insulin antibodies or beta cell antibodies and negative HLA association

3

What is Type II associated with?

Hyperosmotic hyperglycemia syndrome but not DKA

4

Recommendation I for treatment of DM-II?

When diet, exercise, weight loss and life style changes are not adequate to improve hyperglycemia then add oral pharmacologic therapy

5

Recommendation II for treatment of DM-II?

Initial pharmacologic therapy should be monotherapy with metformin

6

Recommendation II for treatment of DM-II?

When lifestyle changes and monotherapy with metformin fail to control hyperglycemia then add a second drug to metformin

7

What is the primary factor in determining fasting plasma glucose levels?

Hepatic glucose production (gluconeogenesis)

8

What do sulfonylurea agents mainly control?

Fasting (basal) hyperglycemia by raising basal levels of insulin

9

What does Acarbose do?

Effects postprandial response by delaying absorption of carbohydrates

10

What do short acting sulfonylurea agents such as Miglitol and nateglinide do?

Some effect on postprandial response but less ability to reduce overall A1c and little effect on basal sugar

11

What do metformin and TZD's effect?

Production and clearance of glucose by effect on hepatic gluconeogenesis and effect on glucose uptake at muscle and adipose respectively

12

When is metformin and TZD's have their major effect?

Fasting glucose and some effect on post prandial as well

13

When do incretin agents, DPP-4 inhibitors and incretin mimetics have their effect?

Fasting and post prandial blood sugar levels

14

When do SGLT-2 inhibitors have their effect?

Both fasting and postprandial glucose levels

15

When do incretin and amylin mimetics have their effect?

Fasting and postprandial glucose levels

16

What drugs have peak affect 4-6 hrs?

Aspart
Lispro
Glulisine

17

What drugs have peak affect at 5-8 hrs?

Regular insulin

18

What drugs have peak affect at 10-18 hrs?

NPH

19

What drugs have peak affect at 16-20 hrs?

Ultralente

20

What drugs have peak affect at 24 hrs?

Glargine
Detemir