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Flashcards in digestive process Deck (25):
1

protein has no taste

- due no chymotrypsin, trypsin in saliva
- trypsin essential

2

essential in stomach is

- intrinsic factor
- absorb B12 in the terminal ileum

3

pancreas

- essential
- lipase
- amylase

4

gallbladder

- bile and lipase for fat absorption
- starve to death

5

small bowel

- disaccharidases (lactase, lactose intolerance; sucrase, sucrose intolerance; maltase 2 glucose breakdown, trehalase 3 glucose breakdown)
- only MONOSACCHARIDES CAN BE ABSORBED by FACILITATED DIFFUSION

6

driving the entire absorption

- NaKATPase (active transport splitting energy)

7

not dependent in sodium reabsorption

- FRUCTOSE (independent of sodium reabsorption)

8

which of the following does not affect secondary active transport

- INSULIN
- it does not affect glucose absorption in GUT and KIDNEY

9

INSULIN

- affects transport in adipose tissue and resting muscles

10

AMINO ACIDS

- are transported by SECONDARY ACTIVE TRANSPORT liked to SODIUM

11

absorption of lipids
TRIGYCERIDE

- bile micelles (emulsify)
- pancreatic lipase will absorb it into 2 free fatty acids and position 2 monoglyceride

12

absorption of fats is by

- diffusion
- chylomicrons brings the fat to thoracic duct for mixing

13

absorption of fats
lipase breaksdown

- triglyceride

14

absorption of fats
cholesterol esterase

- breaks up into cholesterol and free fatty acid
reesterified into chylomicron that goes into the lymph and dumps it into circulation by the process of DIFFUSION

15

ABSORPTION
duodenum

- most divalent ions (Fe, Ca, Mg)
- water soluble vitamins
- Fe+
- Mg+
- Ca+
- celiac disease (IRON DEFICIENCY)
- chronic pancreatitis(NO IRON DEFICIENCY because the don't need pancreatic enzymes)
- stool are greasy, foul, floating etc.
- malabsorption of fat soluble vitamins ADEK
- weight loss due to fat malabsorption
- osteoporosis Vit D malabsorption
- easy bruising

16

CELIAC DISEASE vs CHRONIC PANCREATITIS

- celiac disease (IRON DEFICIENCY)
- chronic pancreatitis (NO IRON DEFICIENCY because the don't need pancreatic enzymes)

17

JEJUNUM

- overall
- net absorption of water and electrolytes
- site where HCO3 IS ABSORBED

18

distal ILEUM

- BILE SALTS ABSORPTION
- VITAMIN B12 and INTRINSIC FACTOR ABSORPTION
- ONLY IN ILEUM

19

COLON

- only site excrete 100% POTASSIUM; HCO3 (duodenum also excrete and absorb)
- NO DIGESTION PROCESS/ENZYME
- DIARRHEA
- site of action for ALDOSTERONE
- absorb most of the water

20

case:
site of development of diarrhea where patient presents with low serum potassium and HCO3

- COLON

21

ALDOSTERONE works

- on the COLON
- and DISTAL TUBULE

22

case:
patient with HEMOCHROMATOSIS site of defect

- DUODENUM

23

case:
IRON OVERLOAD
HFe gene site of defect

- DUODENUM

24

case:
IRON deposition in the heart, liver, skin, gonads site of defect

- DUODENUM

25

case:
difference between
CHRONIC PANCREATITIS
vs
WHIPPLES DISEASE
TROPICAL SPRUE
CELIAC DISEASE

- DUODENAL MALABSORPTION OF IRON