DILTIAZEM (Cardizem®) Flashcards
1
Q
Generic/Trade Name
DILTIAZEM
A
Cardizem®
2
Q
Generic/Trade Name
Cardizem®
A
DILTIAZEM
3
Q
Drug Classification:
A
Ca2+ Channel Blocker
4
Q
Mechanism of Action:
A
- Ca2+ Channel Blocker ⇒
- peripheral and coronary vasodilation
- slowed conduction through AV node
- (-) inotropy
- decreased myocardial O2 demand
5
Q
Pharmacokinetics
A
Onset of Action = 3 minutes
Peak Effects = 7 minutes
Duration of Effect = 1-3 hours
Half-Life = 2 hours
6
Q
Indications/Field Use:
A
- Rapid ventricular rates associated with a-fib, a-flutter
- PSVT refractory to adenosine
7
Q
Contraindications:
A
- Severe hypotension
- cardiogenic shock
- CHF
- Wide complex tachycardia
- WPW
8
Q
Side Effects/Adverse Reactions:
A
- N+V
- dizziness
- HA
- bradycardia
- heart block
- hypotension
- asystole
9
Q
ADULT DOSE:
A
(ADULT): 1st dose - 0.25mg/kg IVP(IO) over 2min (usual dose 15-20mg)
2nd dose - 0.35mg/kg Maintenance dose: 5-15mg/hr
10
Q
PEDI DOSE:
A
Not for Pediatric Patients
11
Q
Precautions:
A
- May cause systemic hypotension
- monitor BP
- have CaCl2 available
- Must be discarded after one month without refrigeration
12
Q
DILTIAZEM (Cardizem®)
Drug-Drug Interactions:
A
Do not give to Pt. receiving IV β blockers, will increase risk of CHF, bradycardia
13
Q
DILTIAZEM (Cardizem®)
Drug-Drug Interactions:
A
Do not give to Pt. receiving IV β blockers, will increase risk of CHF, bradycardia
