Drug Action Flashcards by Christina Jeong | Brainscape

Q

fraction of receptors occupied by drug A (equation)

A

1/ ( 1+ Ka/[A] )

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Q

effect of positive allosteric modulator

A

increase potency

binds elsewhere

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Q

efficacy of a drug: Kactive to Kinactive relationship:

Kactive < Kinactive
Kactive = Kinactive
Kactive > Kinactive

A

agonist, partial agonist
competitive inhibitor
inverse agonist

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Q

effect of negative modulation

A

decrease in potency, efficacy, or both

binds elsewhere

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