1
Q
Can drugs that bind to proteins reach their sites of action?
A
No. Only unbound drugs can.
2
Q
What factors affect drug distribution?
A
Plasma protein binding Tissue perfusion Membrane characteristics (eg blood brain barrier) Transport mechanisms Disease/Other drugs Elimination
3
Q
Name 3 ways drugs are excreted by the kidneys
A
Glomerular Filtration
Passive tubular re absorption
Active Tubular secretion
Principles of Health and Disease
flashcards
Decks in class (17)
# Cards
-
Hypersensitivity and Autoimmunity14
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Drug Absorption14
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Drug Distribution3
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Drug metabolism8
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Drug Delivery2
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ADRs14
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Clinical Trial Design6
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Storing and Using genetic information12
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DNA mutations and Analysis11
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Chromosomes and Cell Division13
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Meiosis and Chromosome abnormalities11
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Genetic Disease7
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Tumour Pathology30
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Introduction to Bacteria, fungi and parasites9
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Principles of immunisation2
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Bacteria7
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Acute inflammation5
