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Human disease and therapeutics 2020 > Drug enforcement > Flashcards

Drug enforcement Flashcards

1
Q

What is the mission of the DEA?

A

-Enforce the controlled substances laws and regulations of the USA

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2
Q

What does the DEA address?

A

-Issues of illegal growing, manufacturing or distribution both domestically and internationally

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3
Q

What does the Drug Czar head up?

A

-ONDCP (Office of National Drug Control Policy)

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4
Q

What does the Drug Czar oversee?

A

activities and budgets of:

  • DEA
  • NIDA (National Institute of Drug Abuse)
  • NIAAA
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5
Q

What department oversees programs that deal with illicit and prescribed Scheduled drugs?

A

-DEA

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6
Q

What are four programs that the DEA oversees?

A
  • Drug eradication
  • Drug education
  • Assist state and local agencies, civic groups, and school systems to combat drug abuse
  • Helps secure borders against drug trafficking
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7
Q

What branch of government is the drug czar?

A

-Executive branch

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8
Q

What is a schedule I drug?

A
  • No currently accepted medical use in the US

- High potential for abuse

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9
Q

What is a schedule II drug?

A

High potential for abuse

-Has approved medical use

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10
Q

What are examples of schedule I drugs?

A
  • Heroin
  • LSD
  • Marijuana
  • Ecstasy
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11
Q

What are examples of schedule II drugs?

A
  • Hydrocodone (Vicodin, Lortab)
  • Fentanyl (Sublimaze)
  • Stimulants (amphetamines)
  • Methadone
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12
Q

What is a schedule III drug?

A
  • Moderate or low physical dependence

- Less potential for abuse

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13
Q

What are examples of schedule III drugs?

A
  • Buprenorphine

- Ketamine

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14
Q

What is a schedule IV drug?

A

-Low potential for abuse

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15
Q

What are examples of schedule IV drugs?

A

-Alprazolam (Xanax)
-Midazolam (Versed)
(Most Benzos)
-Tramadol (Ultram)

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16
Q

What is a schedule V drug?

A
  • Low abuse potential

- Limited quantities of certain narcotics

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17
Q

Examples of Schedule V drugs?

A

-Robitussin

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18
Q

DOPL is a legislatively created database to track and collect data on what?

A

-Dispensing of schedule II-V drugs

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19
Q

What is the purpose of DOPL and the UCSD?

A

-Identify over-utilization, misuse and over-prescribing of controlled substances throughout the state

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20
Q

Outpatient pharmacies report dispensing of scheduled drugs within what time frame?

A

-7 days and the data are posted within 24 hrs after receipt

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21
Q

What is not required to report to the UCSD (Utah controlled substance database)?

A
  • Prescriptions at federal facilities (VA, military)
  • Out of state pharmacies
  • Pharmacies servicing in-patient populations (hospital)
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22
Q

In prescriptions what does a.c. (ante cibum) mean?

A

-Before meals

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23
Q

In prescriptions what does ad.lib (ad libitum) mean?

A

-Use freely

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24
Q

In prescriptions what does aq (aque) mean?

A

-Water

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25
Q

What does bis mean in a prescription?

A

-Twice

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26
Q

What does bid mean in a prescription?

A

-Twice daily

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27
Q

What does c.f mean in a prescription?

A

-with food

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28
Q

What does dc mean in a prescription?

A

-Discontinue

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29
Q

what does h (hora) mean in a prescription?

A

-hour

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30
Q

What does noct (nocta) mean in a prescription?

A

-at night

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31
Q

What does p.c. (post cibum) mean in a prescription?

A

-after meals

32
Q

What does prn (pro re nata) mean in a prescription?

A

-as needed

33
Q

What does p.o. (per os) mean in a prescription?

A

-by mouth

34
Q

What does q (quaque) mean in a prescription?

A

-every

35
Q

What does q.h. mean in a prescription?

A

-every hour

36
Q

What does q.d. mean in a prescription?

A

every day

37
Q

What does .q.i.d (quates in die) mean in a prescription?

A

-4 x per day

38
Q

What does s (sina) mean in a prescription?

A
  • without

- w/o also means without

39
Q

What does sig mean in a prescription?

A

-write on the label

40
Q

What does stat mean in a prescription?

A

-immediately

41
Q

What does t.i.d mean in a prescription?

A

-Three times daily

42
Q

What does w mean in a prescription?

A

-with

43
Q

What is an FDA approved cannabinoid agonist?

A

-Marinol (dronabinol)

44
Q

What is Marinol used for?

A
  • Increases appetite
  • Anti-nausea
  • CB1 agonist
  • Synthetic THC/prescription
45
Q

What are proposed THC/marijuana uses?

A
  • anti-nausea
  • increase appetite
  • glaucoma-reduce intraocular pressure
  • chronic pain
46
Q

What is CBD (cannabidol)?

A
  • Analog promoted as anti seizure

- Not as addicting as THC

47
Q

What is (Acomplia) Rimonabant?

A

CB1 antagonist

-Used to treat obesity by reducing apetite

48
Q

What do “spice” products contain?

A

-Cannabinoid agonists/antagonists and other drugs

49
Q

who evaluates, coordinates, and oversees both international and domestic anti-drug efforts?

A

the drug czar

50
Q

the UCSD is a legistlatively created database to track and collect data on dispensing of schedule ___ drugs by retail, institutional, and outpatient hospital pharmacies

A

II-V

51
Q

what is the role of the DOPL in controlling dental licensing?

A
  • manages unprofessional conduct (false advertising and maintaining proper conditions related to practice)
  • manage proper CE observance
52
Q

what is amotivation syndrome?

A
  • lose a sense of ambition

- common affect of marijuana

53
Q

what is the endogenous ligand in marijuana?

A

-anandamide (natural neurotransmitter)

54
Q

what are the 3 main mechanisms of marijuana?

A
  • activates cannabinoid receptors
  • bronchodilator
  • vasodilator
55
Q

what are the cannabinoid receptors that marijuana activates, where are they located, and what do they do?

A
  • CB1 - mostly CNS and mediates abuse problems

- CB2 - mostly peripheral and mediates inflammatory effects

56
Q

can marijuana cause tolerance and dependence?

A

yes

57
Q

T or F:

many cannabinoid agonists are developed for street drugs

A

true

58
Q

what is the legal status of marijuana?

A
  • schedule I federal laws

- varies according to state laws (range from illegal, medical marijuana, to legalization)

59
Q

why was the approval of rimonabant withdrawn in europe?

A

-due to depression/suicide

60
Q

is “spice” legal?

A

-it was originally legal, but has since been outlawed

61
Q

what schedule drug is “spice”?

A

-schedule I

62
Q

what are the side effects of spice?

A
  • withdrawals
  • attention disruptions
  • induced psychosis with strong marijuana
  • anxiety disorders
63
Q

what is MUD?

A

-marijuana use disorder

64
Q

___% of those who use marijuana have a form of MUD

A

9%

65
Q

if marijuana users begin using <18 years old, the likelihood of MUD increases ___x

A

4-7x

66
Q

how many people in the US had MUD in 2015?

A

4 million

67
Q

___ are drugs that alter fetal development when used during pregnancy by the mother

A

teratogens

68
Q

when used during pregnancy, ___ dramatically increases the likelihood that female offspring would develop cervical cancer especially when young, although the incidence of this is quite rare

A

diethylstilbesterol

69
Q

what are the 5 FDA classifications for teratogens?

A

A, B, C, D, X

70
Q

what is a category A teratogen?

A

no evidence the drug is a teratogen in either humans of lab animals

71
Q

what is a category B teratogen?

A

no animal evidence, not well tested in humans

72
Q

what is a category C teratogen?

A

no good animal or human testing done

73
Q

what is a category D teratogen?

A

animal testing suggests it is teratogenic, but not well studied in humans

74
Q

what is a category X teratogen?

A

definitely shown to be teratogenic in humans

75
Q

what is an example of a category X teratogen?

A

isotretinoin (accutane)

Human disease and therapeutics 2020 (60 decks)

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