Drug Interactions Flashcards Preview

AB 3rd Year General > Drug Interactions > Flashcards

Flashcards in Drug Interactions Deck (10):
1

what decreases efficacy of clopidogrel?

PPIs

2

what, alongside SU, can increase hypos?

ACEs

3

what food/OTC are cytochrome P450 inducers?

grapefruit juice
St Jons Wart

4

what herbal remedies are anticoagulants? uses?

saw pilmetto- BPH
gingko biloba - memory

5

what should not be given in asthma?

Beta blockers

6

asthma Tx?

SABA
+ICS
+ leukotrine receptor agonist
LABA + ICS + SABA
combined LABA and ICS

7

what drugs worsen HF?

TZD
NSAIDs
cox 2 inhibitors

8

if using a PPI, what may occur to drug absorption? why?

absorbed basic drugs more readily
senescence of parietal cells so stomach is more basic

9

what binds acidic drugs?

albumin

10

what binds alkali drugs?

alpha 1 glycoprotein