Drugs

Question 1

Amiodarone: adverse effects

Answer 1

Question 2

Ciclosporin : SE

Answer 2

Adverse effects of ciclosporin (note how everything is increased - fluid, BP, K+, hair, gums, glucose)
nephrotoxicity
hepatotoxicity
fluid retention
hypertension
hyperkalaemia
hypertrichosis
gingival hyperplasia
tremor
impaired glucose tolerance
hyperlipidaemia
increased susceptibility to severe infection

Question 3

Digoxin and digoxin toxicity

Answer 3

Mechanism of action
decreases conduction through the atrioventricular node which slows the ventricular rate in atrial fibrillation and flutter
increases the force of cardiac muscle contraction due to inhibition of the Na+/K+ ATPase pump. Also stimulates vagus nerve

Question 4

Dopamine receptor agonists

Answer 4

Question 5

Drug monitoring

Answer 5

Question 6

Drug-induced urinary retention

Answer 6

Drug-induced urinary retention
The following drugs may cause urinary retention:
* tricyclic antidepressants e.g. amitriptyline
* anticholinergics e.g. antipsychotics, antihistamines
* opioids
* NSAIDs
* disopyramide

Question 7

Drugs causing lung fibrosis

Answer 7

Question 8

Drugs causing ocular problems

Answer 8

Question 9

Macrolides - Eryhtromycin, Clarithromycin

Answer 9

Question 10

Phosphodiesterase type V inhibitors

Answer 10

Question 11

Prescribing in patients with renal failure

Answer 11

Question 12

Side-effects of common drugs: anti-hypertensives

Answer 12

Question 13

Tuberculosis: drug side-effects and mechanism of action

Answer 13